Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.
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Overview
publication date
- January 2000
published in
- Molecular cell Journal
has subject area
- Cell Differentiation
- Cell Transformation, Neoplastic
- Cholecalciferol
- DNA-Binding Proteins
- Dimerization
- Gene Expression Regulation, Leukemic
- Leukemia, Promyelocytic, Acute
- Models, Genetic
- Monocytes
- Neoplasm Proteins
- Nuclear Receptor Co-Repressor 2
- Oncogene Proteins, Fusion
- Protein Binding
- Receptors, Retinoic Acid
- Recombinant Fusion Proteins
- Repressor Proteins
- Retinoid X Receptors
- Signal Transduction
- Transcription Factors
- Transcription, Genetic
- Translocation, Genetic
- Tretinoin