Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations. uri icon

authors

  • Houlden, H
  • Swash, M
  • Scaravilli, F
  • Holton, J L
  • Lashley, T
  • Tomita, T
  • Hashimoto, T
  • Verkkoniemi, A
  • Kalimo, H
  • Somer, M
  • Paetau, A
  • Baker, M
  • Martin, J J
  • Van Broeckhoven, C
  • Todd Golde, MD, PhD
  • Hardy, J
  • Haltia, M
  • Revesz, T
  • McGowan, E
  • Lewis, P
  • Hutton, M
  • Crook, R
  • Wood, N W
  • Kumar-Singh, S
  • Geddes, J

publication date

  • January 2000