authors
- Weggen, S
- Bulter, T
- Kang, D E
- Marquez-Sterling, N
- Todd Golde, MD, PhD
- Koo, E H
- Eriksen, J L
- Das, P
- Sagi, S A
- Wang, R
- Pietrzik, C U
- Findlay, K A
- Smith, T E
- Murphy, M P
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.
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Overview
publication date
- January 1, 2001
published in
- Nature Journal
has subject area
- Alzheimer Disease
- Amyloid Precursor Protein Secretases
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Animals
- Anti-Inflammatory Agents, Non-Steroidal
- Aspartic Acid Endopeptidases
- Brain
- CHO Cells
- Cricetinae
- Disease Models, Animal
- Endopeptidases
- Enzyme-Linked Immunosorbent Assay
- Humans
- Ibuprofen
- Indomethacin
- Mass Spectrometry
- Mice
- Mice, Transgenic
- Peptide Fragments
- Prostaglandin-Endoperoxide Synthases
- Sulindac
- Tumor Cells, Cultured