authors
- Eriksen, Jason L
- Koo, Edward H
- Todd Golde, MD, PhD
- Sagi, Sarah A
- Smith, Tawnya E
- Weggen, Sascha
- Das, Pritam
- McLendon, D C
- Ozols, Victor V
- Jessing, Kevin W
- Zavitz, Kenton H
NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo.
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Overview
publication date
- January 2003
published in
has subject area
- Alzheimer Disease
- Amyloid Precursor Protein Secretases
- Amyloid beta-Peptides
- Animals
- Anti-Inflammatory Agents, Non-Steroidal
- Aspartic Acid Endopeptidases
- Brain
- Cell Line
- Endopeptidases
- Female
- Flurbiprofen
- Humans
- Meclofenamic Acid
- Mice
- Mice, Transgenic
- Peptide Fragments
- Protease Inhibitors
- Stereoisomerism