PTHrP signaling targets cyclin D1 and induces osteoblastic cell growth arrest.
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Overview
publication date
- January 1, 2005
published in
has subject area
- 3T3 Cells
- Animals
- Blotting, Northern
- Blotting, Western
- Butadienes
- Cell Cycle
- Cell Differentiation
- Cell Proliferation
- Cell Separation
- Cells, Cultured
- Cyclic AMP
- Cyclic AMP-Dependent Protein Kinases
- Cyclin D1
- Cyclin-Dependent Kinase Inhibitor p16
- Densitometry
- Dose-Response Relationship, Drug
- Down-Regulation
- Electrophoresis, Polyacrylamide Gel
- Enzyme Inhibitors
- Enzyme-Linked Immunosorbent Assay
- Flow Cytometry
- G1 Phase
- Gene Silencing
- Glutathione Transferase
- Histones
- Immunoprecipitation
- MAP Kinase Signaling System
- Mice
- Models, Biological
- Nitriles
- Osteoblasts
- Parathyroid Hormone-Related Protein
- Phosphorylation
- Protein Kinase C
- Proto-Oncogene Proteins c-jun
- RNA
- RNA, Small Interfering
- Retinoblastoma Protein
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Time Factors
- Up-Regulation