C-terminal PAL motif of presenilin and presenilin homologues required for normal active site conformation.
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Overview
publication date
- January 1, 2005
published in
- Journal of neurochemistry Journal
has subject area
- Amino Acid Motifs
- Amyloid Precursor Protein Secretases
- Aspartic Acid Endopeptidases
- Binding Sites
- Cell Line
- Endopeptidases
- Enzyme Inhibitors
- Enzyme-Linked Immunosorbent Assay
- Humans
- Hydrolysis
- Membrane Proteins
- Mutation
- Peptide Hydrolases
- Plasmids
- Presenilin-1
- Protein Binding
- Protein Conformation
- Structure-Activity Relationship
- Transfection