The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis.
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Overview
publication date
- January 2008
published in
- Annals of neurology Journal
has subject area
- Amyotrophic Lateral Sclerosis
- Animals
- Astrocytes
- Central Nervous System
- Dinoprostone
- Disease Models, Animal
- Disease Progression
- Gene Expression Regulation, Enzymologic
- Humans
- Inflammation
- Inflammation Mediators
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Phenotype
- Receptors, Prostaglandin E
- Receptors, Prostaglandin E, EP2 Subtype
- Spinal Cord
- Superoxide Dismutase
- Up-Regulation