authors
- Stewart, M David
- Pask, Andrew J
- Schwartz, Robert J
- Conn, P Michael
- Behringer, Richard R
- Deng, Jian Ming
- Stewart, C Allison
- Mullen, Rachael D
- Wang, Ying
- Lopez, Suhujey
- Myrna Katalina Serna, MD, MPH
- Huang, Cheng-Chiu
- Janovick, Jo Ann
Mice harboring Gnrhr E90K, a mutation that causes protein misfolding and hypogonadotropic hypogonadism in humans, exhibit testis size reduction and ovulation failure.
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Overview
publication date
- August 23, 2012
published in
has subject area
- Amino Acid Substitution
- Animals
- Anovulation
- Base Sequence
- Estrous Cycle
- Female
- Gene Expression Regulation
- Gonadotropins
- Homozygote
- Humans
- Hypogonadism
- Luteinization
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Molecular Sequence Data
- Mutation
- Organ Size
- Proteostasis Deficiencies
- Receptors, LHRH
- Testis