authors
- Gong, Bing
- Sauve, Anthony A
- Pasinetti, Giulio M
- Pan, Yong
- Vempati, Prashant
- Zhao, Wei
- Knable, Lindsay
- Ho, Lap
- Wang, Jun
- Sastre, Magdalena
- Ono, Kenjiro
Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models.
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Overview
publication date
- January 9, 2013
published in
- Neurobiology of aging Journal
has subject area
- Alzheimer Disease
- Amyloid Precursor Protein Secretases
- Animals
- Aspartic Acid Endopeptidases
- Cells, Cultured
- Cognition Disorders
- Disease Models, Animal
- Gene Expression Regulation
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mitochondria
- Niacinamide
- Organ Culture Techniques
- Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
- Pyridinium Compounds
- Transcription Factors
- Up-Regulation