γ-Secretase inhibitors and modulators.

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• Overview
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• Research
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Overview

authors

• Todd Golde, MD, PhD
• Koo, Edward H
• Felsenstein, Kevin M
• Osborne, Barbara A
• Miele, Lucio

publication date

• January 1, 2013

published in

• Biochimica et biophysica acta  Journal

has subject area

• Alzheimer Disease
• Amyloid Precursor Protein Secretases
• Amyloid beta-Protein Precursor
• Binding Sites
• Clinical Trials as Topic
• Drug Design
• Humans
• Neoplasms
• Protease Inhibitors
• Protein Binding
• Protein Subunits
• Proteolysis
• Signal Transduction
• Structure-Activity Relationship
• Substrate Specificity

Research

Keywords

• Alzheimer's disease
• Cancer
• γ-Secretase inhibitor
• γ-Secretase modulator

Identity

Digital Object Identifier (DOI)

• https://doi.org/10.1016/j.bbamem.2013.06.005

PubMed ID

• 23791707

Additional Document Info

start page

• 2898

end page

• 907

volume

• 1828

issue

• 12