An excess of risk-increasing low-frequency variants can be a signal of polygenic inheritance in complex diseases. uri icon

authors

  • Chan, Yingleong
  • Daly, Mark J
  • Neale, Benjamin M
  • Salem, Rany M
  • Hirschhorn, Joel N
  • Elaine Lim, PhD
  • Sandholm, Niina
  • Wang, Sophie R
  • McKnight, Amy Jayne
  • Ripke, Stephan

publication date

  • January 1, 2014