authors
- Lowe, Stephen L
- Royalty, Jane
- Tauscher-Wisniewski, Sitra
- Wong, Conrad J
- Witcher, Jennifer
- Gonzales, Celedon R
- Dickinson, Gemma L
- Bell, Robert L
- Rorick-Kehn, Linda
- Weller, MaryAnn
- Stoltz, Randall R
Safety, tolerability, and pharmacokinetic evaluation of single- and multiple-ascending doses of a novel kappa opioid receptor antagonist LY2456302 and drug interaction with ethanol in healthy subjects.
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Overview
publication date
- January 1, 2014
published in
- Journal of clinical pharmacology Journal
has subject area
- Administration, Oral
- Adrenocorticotropic Hormone
- Adult
- Alcohol Drinking
- Benzamides
- Cognition
- Cross-Over Studies
- Double-Blind Method
- Drug Interactions
- Ethanol
- Female
- Healthy Volunteers
- Humans
- Hydrocortisone
- Luteinizing Hormone
- Male
- Middle Aged
- Narcotic Antagonists
- Postural Balance
- Prolactin
- Pyrrolidines
- Reaction Time
- Receptors, Opioid, kappa