Cancer-associated mutants of RNA helicase DDX3X are defective in RNA-stimulated ATP hydrolysis.
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Overview
publication date
- January 1, 2015
published in
- Journal of molecular biology Journal
has subject area
- Adenosine Triphosphate
- Binding Sites
- Cerebellar Neoplasms
- Child
- Crystallization
- Crystallography, X-Ray
- DEAD-box RNA Helicases
- Genetic Complementation Test
- Humans
- Hydrolysis
- Medulloblastoma
- Models, Molecular
- Mutagenesis, Site-Directed
- Mutation
- Nuclear Magnetic Resonance, Biomolecular
- Protein Biosynthesis
- Protein Conformation
- RNA
- Schizosaccharomyces