NLRP3 inflammasome activation by mitochondrial reactive oxygen species plays a key role in long-term cognitive impairment induced by paraquat exposure.
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Overview
publication date
- June 6, 2015
published in
- Neurobiology of aging Journal
has subject area
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- Animals
- Carrier Proteins
- Cognition Disorders
- Disease Models, Animal
- Electron Transport Complex I
- Electron Transport Complex IV
- Herbicides
- Humans
- Hydrogen Peroxide
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mitochondria
- NLR Family, Pyrin Domain-Containing 3 Protein
- Nerve Tissue Proteins
- Oxidative Stress
- Paraquat
- Presenilin-1
- Reactive Oxygen Species