Xanthine oxidase is hyper-active in Duchenne muscular dystrophy.

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Overview

authors

• Lindsay, Angus
• McCourt, Preston M
• Karachunski, Peter
• Lowe, Dawn A
• Ervasti, James M

publication date

• January 1, 2018

published in

• Free radical biology & medicine  Journal

has subject area

• Adolescent
• Allopurinol
• Animals
• Biomarkers
• Case-Control Studies
• Creatinine
• Dystrophin
• Enzyme Inhibitors
• Gene Expression Regulation
• Humans
• Male
• Mice
• Mice, Inbred mdx
• Muscle Contraction
• Muscle, Skeletal
• Muscular Dystrophy, Animal
• Muscular Dystrophy, Duchenne
• Oxypurinol
• Sarcoglycans
• Tyrosine
• Utrophin
• Xanthine Oxidase
• Xanthopterin
• Young Adult

Research

Keywords

• Allopurinol
• Duchenne muscular dystrophy
• Dystrophin
• Gene therapy
• Isoxanthopterin
• Mdx
• Oxidative stress
• Pterin
• Xanthine oxidase

Identity

Digital Object Identifier (DOI)

• https://doi.org/10.1016/j.freeradbiomed.2018.10.404

PubMed ID

• 30312761

Additional Document Info

start page

• 364

end page

• 371