authors
- Niu, Chenchen
- Sopher, Bryce L
- Brooks, Brian P
- Swayze, Eric E
- Bennett, C Frank
- Al La Spada, MD, PhD
- Prakash, Thazah P
- Kim, Aneeza
- Quach, John L
- Huryn, Laryssa A
- Yang, Yuechen
- Lopez, Edith
- Jazayeri, Ali
- Hung, Gene
Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7.
- Overview
- Identity
- Additional Document Info
- View All
Overview
publication date
- January 1, 2018
published in
- Science translational medicine Journal
has subject area
- Animals
- Ataxin-7
- Chromatin Assembly and Disassembly
- Disease Models, Animal
- Disease Progression
- Epigenesis, Genetic
- Gene Expression Regulation
- Humans
- Intravitreal Injections
- Mice
- Mutant Proteins
- Oligonucleotides, Antisense
- Peptides
- Phenotype
- Photoreceptor Cells, Vertebrate
- Protein Aggregates
- Retina
- Retinal Degeneration
- Spinocerebellar Ataxias
- Vision, Ocular