Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. uri icon

authors

  • Kunkle, Brian W
  • Amlie-Wolf, Alexandre
  • Benito, Yolanda A
  • Holmes, Clive
  • Karamujić-Čomić, Hata
  • Frosch, Matthew P
  • Thonberg, Hakan
  • Maier, Wolfgang
  • Roshchupkin, Gennady
  • Ghetti, Bernardino
  • Giedraitis, Vilmantas
  • Kawalia, Amit
  • Bellenguez, Céline
  • Li, Shuo
  • Huebinger, Ryan M
  • Kilander, Lena
  • Moebus, Susanne
  • Hernández, Isabel
  • Kamboh, M Ilyas
  • Brundin, RoseMarie
  • Turton, James
  • Yang, Qiong
  • Katz, Mindy J
  • Frizatti, Aura
  • Concari, Letizia
  • Lord, Jenny
  • Beiser, Alexa S
  • Keene, C Dirk
  • Helisalmi, Seppo
  • Kloszewska, Iwona
  • Kukull, Walter A
  • Koivisto, Anne Maria
  • Lynch, Aoibhinn
  • Tarraga, Lluís
  • Chouraki, Vincent
  • Larson, Eric B
  • Haapasalo, Annakaisa
  • Lawlor, Brian
  • Mosley, Thomas H
  • Lipton, Richard B
  • Solfrizzi, Vincenzo
  • Gill, Michael
  • Longstreth, W T
  • Montine, Thomas J
  • Frisardi, Vincenza
  • Martin, Eden R
  • Diez-Fairen, Monica
  • Rivadeneira, Fernando
  • Petersen, Ronald C
  • Deramecourt, Vincent
  • Alvarez, Ignacio
  • Salani, Francesca
  • Ciaramella, Antonio
  • Boerwinkle, Eric
  • Reiman, Eric M
  • Fievet, Nathalie
  • Sleegers, Kristel
  • Rotter, Jerome I
  • Reisch, Joan S
  • Hanon, Olivier
  • Cupidi, Chiara
  • Andre Uitterlinden, A G
  • Royall, Donald R
  • Dufouil, Carole
  • Maletta, Raffaele Giovanni
  • de Rojas, Itziar
  • Sano, Mary
  • Badarinarayan, Nandini
  • Brice, Alexis
  • Cecchetti, Roberta
  • George-Hyslop, Peter St
  • Ritchie, Karen
  • Tsolaki, Magda
  • Tsuang, Debby W
  • Dubois, Bruno
  • Craig, David
  • Wu, Chuang-Kuo
  • Soininen, Hilkka
  • Jakobsdottir, Johanna
  • Avramidou, Despoina
  • Albin, Roger L
  • Fratiglioni, Laura
  • Germanou, Antonia
  • Liana Apostolova, MD, MSc, FAAN
  • Keller, Lina
  • Koutroumani, Maria
  • Arnold, Steven E
  • Panza, Francesco
  • Gkatzima, Olymbia
  • Hamilton-Nelson, Kara L
  • Asthana, Sanjay
  • Hannequin, Didier
  • Whitehead, Patrice
  • Atwood, Craig S
  • Caffarra, Paolo
  • Hampel, Harald
  • Quintela, Inés
  • Carracedo, Ángel
  • Lannfelt, Lars
  • Rubinsztein, David C
  • Moreno-Grau, Sonia
  • Barnes, Lisa L
  • Pasquier, Florence
  • Frölich, Lutz
  • Barral, Sandra
  • Bernadette McGuinness, MD, PhD
  • Beach, Thomas G
  • Johnston, Janet A
  • Becker, James T
  • Passmore, Peter
  • Bigio, Eileen H
  • Grenier-Boley, Benjamin
  • Olaso, Robert
  • Schott, Jonathan M
  • Bird, Thomas D
  • Warren, Jason D
  • Boeve, Bradley F
  • Lupton, Michelle K
  • Bowen, James D
  • Proitsi, Petra
  • Boxer, Adam
  • Powell, John F
  • Burke, James R
  • Raybould, Rachel
  • Kauwe, John S K
  • Burns, Jeffrey M
  • Mancuso, Michelangelo
  • Buxbaum, Joseph D
  • Bonuccelli, Ubaldo
  • Cairns, Nigel J
  • McQuillin, Andrew
  • Cao, Chuanhai
  • Livingston, Gill
  • Carlson, Chris S
  • Chen, Yuning
  • Bass, Nicholas J
  • Carlsson, Cynthia M
  • Hardy, John
  • Carney, Regina M
  • Bras, Jose
  • Carrasquillo, Minerva M
  • Guerreiro, Rita
  • Allen, Mariet
  • Chui, Helena C
  • Fisher, Elizabeth
  • Kuzma, Amanda B
  • Masullo, Carlo
  • Crocco, Elizabeth A
  • DeCarli, Charles
  • Bisceglio, Gina
  • Dick, Malcolm
  • Ma, Li
  • Duara, Ranjan
  • Graff-Radford, Neill R
  • Evans, Denis A
  • Hodges, Angela
  • Hiltunen, Mikko
  • Faber, Kelley M
  • Scherer, Martin
  • Fallon, Kenneth B
  • Riemenschneider, Matthias
  • Fardo, David W
  • Heun, Reinhard
  • Farlow, Martin R
  • Kölsch, Heike
  • Ferris, Steven
  • Leber, Markus
  • Morgan, Taniesha
  • Foroud, Tatiana M
  • Heuser, Isabella
  • Galasko, Douglas R
  • Giegling, Ina
  • Gearing, Marla
  • Hüll, Michael
  • Geschwind, Daniel H
  • Gilbert, John R
  • Morris, John
  • Green, Robert C
  • Ahmad, Shahzad
  • Mayo, Kevin
  • Growdon, John H
  • Feulner, Thomas
  • Hamilton, Ronald L
  • Harrell, Lindy E
  • Drichel, Dmitriy
  • Honig, Lawrence S
  • Cushion, Thomas D
  • Huentelman, Matthew J
  • Hollingworth, Paul
  • Vardarajan, Badri N
  • Hulette, Christine M
  • Hyman, Bradley T
  • Marshall, Rachel
  • Jarvik, Gail P
  • Meggy, Alun
  • Abner, Erin
  • Menzies, Georgina E
  • Jin, Lee-Way
  • Leonenko, Ganna
  • Real, Luis M
  • Epelbaum, Jacques
  • Jun, Gyungah R
  • Baldwin, Clinton T
  • Grozeva, Detelina
  • Karydas, Anna
  • Russo, Giancarlo
  • Kaye, Jeffrey A
  • Kim, Ronald
  • Jessen, Frank
  • Kowall, Neil W
  • Vellas, Bruno
  • Hoffmann, Per
  • Kramer, Joel H
  • Vardy, Emma
  • LaFerla, Frank M
  • Jöckel, Karl-Heinz
  • Lah, James J
  • Dichgans, Martin
  • Leverenz, James B
  • Mann, David
  • Levey, Allan I
  • Pickering-Brown, Stuart
  • Sims, Rebecca
  • Boada, Merce
  • Lieberman, Andrew P
  • Klopp, Norman
  • Lunetta, Kathryn L
  • Wichmann, H-Erich
  • Lyketsos, Constantine G
  • Morgan, Kevin
  • Marson, Daniel C
  • Brown, Kristelle
  • Martiniuk, Frank
  • Medway, Christopher
  • Beecham, Gary W
  • Mash, Deborah C
  • Nöthen, Markus M
  • Masliah, Eliezer
  • Hooper, Nigel M
  • McCormick, Wayne C
  • Daniele, Antonio
  • McCurry, Susan M
  • Bayer, Anthony
  • McDavid, Andrew N
  • Gallacher, John
  • Garnier, Jean-Guillaume
  • McKee, Ann C
  • van den Bussche, Hendrik
  • Mesulam, Marsel
  • Brayne, Carol
  • Miller, Bruce L
  • Riedel-Heller, Steffi
  • Miller, Carol A
  • Miller, Joshua W
  • Al-Chalabi, Ammar
  • Morris, John C
  • Harold, Denise
  • Shaw, Christopher E
  • Myers, Amanda J
  • Wiltfang, Jens
  • O'Bryant, Sid
  • Olichney, John M
  • Alvarez, Victoria
  • Parisi, Joseph E
  • Singleton, Andrew B
  • Paulson, Henry L
  • Collinge, John
  • Fitzpatrick, Annette L
  • Perry, William R
  • Mead, Simon
  • Peskind, Elaine
  • Cribbs, David H
  • Rossor, Martin
  • Pierce, Aimee
  • Ryan, Natalie S
  • Poon, Wayne W
  • Nacmias, Benedetta
  • Potter, Huntington
  • Valladares, Otto
  • Sorbi, Sandro
  • Quinn, Joseph F
  • Sacchinelli, Eleonora
  • Raj, Ashok
  • Spalletta, Gianfranco
  • Raskind, Murray
  • Caltagirone, Carlo
  • Bossù, Paola
  • Orfei, Maria Donata
  • Reisberg, Barry
  • Moutet, Marie-Laure
  • Clarke, Robert
  • Reitz, Christiane
  • Smith, A David
  • Ringman, John M
  • Warden, Donald
  • Roberson, Erik D
  • Wilcock, Gordon
  • Rogaeva, Ekaterina
  • Bruni, Amalia Cecilia
  • Rosen, Howard J
  • Gerrish, Amy
  • Gallo, Maura
  • Rosenberg, Roger N
  • Ben-Shlomo, Yoav
  • Sager, Mark A
  • Mecocci, Patrizia
  • Saykin, Andrew J
  • Pastor, Pau
  • Cuccaro, Michael L
  • Vance, Jeffery M
  • Schneider, Julie A
  • Smith, Albert V
  • Schneider, Lori S
  • Slifer, Susan
  • Seeley, William W
  • Smith, Amanda G
  • Sonnen, Joshua A
  • Spina, Salvatore
  • Stern, Robert A
  • Swerdlow, Russell H
  • Tang, Mitchell
  • Tanzi, Rudolph E
  • Qu, Liming
  • Trojanowski, John Q
  • Troncoso, Juan C
  • Van Deerlin, Vivianna M
  • Van Eldik, Linda J
  • Vinters, Harry V
  • Vonsattel, Jean Paul
  • Weintraub, Sandra
  • Welsh-Bohmer, Kathleen A
  • Wilhelmsen, Kirk C
  • Williamson, Jennifer
  • Bis, Joshua C
  • Bacq, Delphine
  • Wingo, Thomas S
  • Woltjer, Randall L
  • Wright, Clinton B
  • Yu, Chang-En
  • Yu, Lei
  • Saba, Yasaman
  • Pilotto, Alberto
  • Bullido, Maria J
  • Peters, Oliver
  • Crane, Paul K
  • Denning, Nicola
  • Bennett, David
  • Bosco, Paola
  • Coto, Eliecer
  • Boccardi, Virginia
  • De Jager, Phil L
  • Lleo, Alberto
  • Warner, Nick
  • Lopez, Oscar L
  • Ingelsson, Martin
  • Deloukas, Panagiotis
  • Jian, Xueqiu
  • Cruchaga, Carlos
  • Graff, Caroline
  • Gwilliam, Rhian
  • Fornage, Myriam
  • Goate, Alison M
  • Sanchez-Juan, Pascual
  • Kehoe, Patrick G
  • Amin, Najaf
  • Ertekin-Taner, Nilifur
  • Berr, Claudine
  • Zhao, Yi
  • Debette, Stéphanie
  • Love, Seth
  • Launer, Lenore J
  • Younkin, Steven G
  • Dartigues, Jean-Francois
  • Corcoran, Chris
  • Ikram, M Arfan
  • Dickson, Dennis W
  • Nicolas, Gael
  • Campion, Dominique
  • Del Zompo, Maria
  • Tschanz, JoAnn
  • Schmidt, Helena
  • Hakonarson, Hakon
  • Clarimon, Jordi
  • Munger, Ron
  • Schmidt, Reinhold
  • Farrer, Lindsay A
  • Van Broeckhoven, Christine
  • C O'Donovan, Michael
  • DeStefano, Anita L
  • Fox, Nick C
  • Jones, Lesley
  • Haines, Jonathan L
  • Deleuze, Jean-Francois
  • Owen, Michael J
  • Gudnason, Vilmundur
  • Mayeux, Richard
  • Escott-Price, Valentina
  • Psaty, Bruce M
  • Ramirez, Alfredo
  • Wang, Li-San
  • Choi, Seung-Hoan
  • Ruiz, Agustin
  • van Duijn, Cornelia M
  • Holmans, Peter A
  • Seshadri, Sudha
  • Williams, Julie
  • Amouyel, Phillippe
  • Schellenberg, Gerard D
  • Lambert, Jean-Charles
  • Pericak-Vance, Margaret A
  • Mateo, Ignacio
  • Hughes, Joseph T
  • Adams, Hieab H
  • Damotte, Vincent
  • Malamon, John
  • Sanchez-Garcia, Florentino
  • Patel, Yogen
  • Brody, Jennifer A
  • Dombroski, Beth A
  • Naranjo, Maria Candida Deniz
  • Daniilidou, Makrina
  • Eiriksdottir, Gudny
  • Mukherjee, Shubhabrata
  • Wallon, David
  • Naj, Adam C
  • Uphill, James
  • Aspelund, Thor
  • Cantwell, Laura B
  • Garzia, Fabienne
  • Galimberti, Daniela
  • Hofer, Edith
  • Butkiewicz, Mariusz
  • Fin, Bertrand
  • Scarpini, Elio
  • Sarnowski, Chloe
  • Boland, Anne
  • Bush, Will S
  • Meslage, Stéphane
  • Kornhuber, Johannes
  • White, Charles C
  • Song, Yuenjoo
  • Barber, Robert C
  • Engelborghs, Sebastiaan
  • Sordon, Sabrina
  • Voijnovic, Dina
  • Adams, Perrie M
  • Vronskaya, Maria
  • Vandenberghe, Rik
  • Mayhaus, Manuel
  • Cupples, L Adrienne
  • Albert, Marilyn S
  • De Deyn, Peter P
  • Gu, Wei
  • Himali, Jayanadra J
  • Beekly, Duane
  • Squassina, Alessio
  • Hartmann, Annette M
  • van der Lee, Sven J
  • Orellana, Adelina
  • Blacker, Deborah
  • Rodriguez-Rodriguez, Eloy
  • Lovestone, Simon
  • Garcia, Melissa E
  • Doody, Rachelle S
  • Munoz-Fernadez, Carmen
  • Sussams, Rebecca
  • Lin, Honghuang
  • Fairchild, Thomas J

publication date

  • January 1, 2019