Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen.
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Overview
publication date
- October 15, 2020
published in
- PLoS genetics Journal
has subject area
- Animals
- BTB-POZ Domain
- CRISPR-Cas Systems
- Elongation Factor 2 Kinase
- Gene Expression Regulation
- Histidine
- Humans
- Kruppel-Like Transcription Factors
- Methyltransferases
- Mice
- Minor Histocompatibility Antigens
- Promoter Regions, Genetic
- Protein Binding
- Protein Processing, Post-Translational
- RAW 264.7 Cells
- Transcription Factors
- Tumor Suppressor Proteins