Keywords AHR, aryl hydrocarbon receptor ANOVA, Analysis of variance BCA, Bicinchoninic acid CYP, cytochrome P450 CYP1A2 Caffeine GI, gastrointestinal tract MROD, 7-methoxyresorufin O-demethylation Rat Rutaecarpine Time-dependent induction intravenous, IV pharmacokinetics, PK