San Diego Resource Center for advancing Alzheimer's Research in Minority Seniors (ARMS)
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ABSTRACT: ADMINISTRATIVE CORE The Administrative Core (AC) will provide administrative and intellectual leadership to implement the theme of the San Diego Resource Center for advancing Alzheimer’s Research in Minority Seniors (SDRC-ARMS). The theme is: To advance transdisciplinary research on Latino Alzheimer’s Disease and Related Dementias (ADRD) to illuminate the role of biological, behavioral, sociocultural and environmental factors in the etiology and outcomes of Latino ADRD. The AC will also coordinate the proposed training activities, and communications and activities between the PIs, the Core Leaders and Core Members, the AD-RCMAR Scientists and their mentors. Further, the AC will connect with the larger UC San Diego (UCSD) and San Diego State University (SDSU) research communities, the UCSD’s Altman Clinical and Translational Research Institute (ACTRI), the Alzheimer’s Disease Cooperative Study (ADCS), and the Shiley-Marcos Alzheimer’s Disease Research Center (ADRC), as well as UCSD and SDSU institutional administrative personnel and NIA staff. The result will be a true transdisciplinary partnership between one of the nation’s leading research institutions (UCSD) and a research-prolific ‘Hispanic Serving Institution’ (SDSU).
ABSTRACT: RESEARCH EDUCATION COMPONENT The overarching goal of the Research Education Component (REC) for the San Diego Resource Center for advancing Alzheimer’s Research in Minority Elders (SDRC-ARMS) is to support mentoring and research education of Latino and other underrepresented scientists whose research is focused on illuminating the role of biological, behavioral, sociocultural and environmental factors in the etiology and outcomes of Latino Alzheimer’s Disease and Related Dementias (ADRD). The REC goals are to: 1) Develop the careers of postdoctoral and junior faculty researchers, as well as mid- career faculty researchers new to ADRD, from Latino and other underrepresented backgrounds, who have demonstrated outstanding research potential and an interest in research focused on understanding factors that affect etiology and outcomes in ADRD; and 2) Provide mentorship, education, career development activities and a broad array of educational and infrastructural resources to enable AD-RCMAR Scientists to enhance their expertise in Latino ADRD research and research methods, successfully complete their research, present and publish their work and attain independent research and/ or career development funding. The SDRC-ARMS will be led by four Principal Investigators (PI), two at each campus: Dr. Moore (UCSD- Geriatrics), González (UCSD-Neurosciences), Gilbert (SDSU-Psychology) and Elder (SDSU/UCSD-Public Health). The four PIs have complementary skills and have collaborated to develop this application using the team science model. The SDRC-ARMS includes three cores: Administrative, Research Education, and Analysis. It is our intention that the SDRC-ARMS and its Cores be composed of investigators who are diverse with respect to their institutional affiliations, disciplines, and research and training skills. This diversity will increase the SDRC-ARMS‘ effectiveness in developing a diverse workforce that can promote advances in Latino ADRD.
PROJECT SUMMARY/ABSTRACT There is an urgent need for mentored training of underrepresented scientists in research on minorities with Alzheimer’s disease and related dementias (ADRD). To address the gap in research and resources, the proposed San Diego Resource Center (SDRC) for advancing Alzheimer’s Research in Minority Seniors (ARMS) aims to identify Latino scientists and others from underrepresented backgrounds who are committed to Latino ADRD research, and to support them in becoming independent career scientists. Our proposed center will focus on transdisciplinary research on Latino Alzheimer’s Disease and Related Dementias (ADRD) to illuminate the role of biological, behavioral, sociocultural and environmental factors in the etiology and outcomes of Latino ADRD. The SDRC-ARMS is a collaboration between the University of California, San Diego (UCSD) and San Diego State University (SDSU). This collaboration leverages both institutions’ strengths: UCSD’s strength in behavioral, sociocultural, systems biology, and multi-layered –omics to understanding ADRD in Latinos and other populations and SDSU’s strengths as a research-prolific Hispanic Serving Institution with robust programs in public health and psychology and vast experience in advancing the careers of Latinos. The SDRC-ARMS’ combined resources provide new and unique transdisciplinary research training opportunities from the bench, to the bedside, and to the community to accelerate scientific discoveries for better brain health of Latinos. The SDRC-ARMS will be led by four Principal Investigators (PI), two at each campus: Dr. Moore (UCSD- Geriatrics), González (UCSD-Neurosciences), Gilbert (SDSU-Psychology) and Elder (SDSU/UCSD-Public Health). The four PIs have complementary skills and have collaborated to develop this application using the team science model. The SDRC-ARMS includes three cores: Administrative, Research Education, and Analysis. It is our intention that the SDRC-ARMS and its Cores be composed of investigators who are diverse with respect to their institutional affiliations, disciplines, and research and training skills. This diversity will increase the SDRC-ARMS‘ effectiveness in developing a diverse workforce that can promote advances in Latino ADRD.
