Molecular neurodegeneration
Journal
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Overview
publication venue for
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Microglial APOE4: more is less and less is more..
18:-.
2023
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Regulation of cortical hyperexcitability in amyotrophic lateral sclerosis: focusing on glial mechanisms..
18:-.
2023
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Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease..
18:-.
2023
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hiPSC-based models to decipher the contribution of human astrocytes to Alzheimer's disease and potential therapeutics..
18:-.
2023
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APOE effects on regional tau in preclinical Alzheimer's disease..
18:-.
2023
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Global neuropathologic severity of Alzheimer's disease and locus coeruleus vulnerability influences plasma phosphorylated tau levels..
17:-.
2022
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17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease are associated with LRRC37A/2 expression in astrocytes..
17:-.
2022
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Imaging tau pathology in Alzheimer's disease with positron emission tomography: lessons learned from imaging-neuropathology validation studies..
17:-.
2022
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Solving neurodegeneration: common mechanisms and strategies for new treatments..
17:-.
2022
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Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis..
17:-.
2022
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Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains..
17:-.
2022
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The landscape of human tissue and cell type specific expression and co-regulation of senescence genes..
17:-.
2022
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TDP-43 Pathology in Alzheimer's Disease..
16:-.
2021
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The informed road map to prevention of Alzheimer Disease: A call to arms..
16:-.
2021
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Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy..
16:-.
2021
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A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis..
16:-.
2021
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A novel systems biology approach to evaluate mouse models of late-onset Alzheimer's disease..
15:-.
2020
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Correction to: Deciphering cellular transcriptional alterations in Alzheimer's disease brains..
15:-.
2020
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Peroxiredoxin 6 mediates protective function of astrocytes in Aβ proteostasis..
15:-.
2020
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Deciphering cellular transcriptional alterations in Alzheimer's disease brains..
15:-.
2020
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Targeting tauopathy with engineered tau-degrading intrabodies..
14:-.
2019
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Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model..
14:-.
2019
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Dural lymphatics regulate clearance of extracellular tau from the CNS..
14:-.
2019
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ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans..
13:-.
2018
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Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases..
13:-.
2018
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Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology..
13:-.
2018
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AMPA-ergic regulation of amyloid-β levels in an Alzheimer's disease mouse model..
13:-.
2018
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α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism..
13:-.
2018
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Glial contributions to neurodegeneration in tauopathies..
12:-.
2017
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Targeting psychologic stress signaling pathways in Alzheimer's disease..
12:-.
2017
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Diurnal oscillation of CSF Aβ and other AD biomarkers..
12:-.
2017
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The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity..
12:-.
2017
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APOE Genotype Differentially Modulates Effects of Anti-Aβ, Passive Immunization in APP Transgenic Mice..
12:-.
2017
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Erratum to: Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation..
12:-.
2017
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Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice..
12:-.
2017
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Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation..
11:-.
2016
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Erratum to: A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease..
11:-.
2016
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A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease..
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2016
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Analysis of in vivo turnover of tau in a mouse model of tauopathy..
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2015
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Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model..
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2015
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Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow..
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2014
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Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2..
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2014
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Conformational templating of α-synuclein aggregates in neuronal-glial cultures..
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2013
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Normal cognition in transgenic BRI2-Aβ mice..
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2013
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In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis..
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2013
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Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis..
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2012
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Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology..
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2012
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Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition..
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2012
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Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice..
7:-.
2012
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Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling..
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2012
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Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer's disease subjects..
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2012
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Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold..
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2011
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Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo..
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2011
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Soluble amyloid-beta, effect on cerebral arteriolar regulation and vascular cells..
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2010
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Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons..
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2009
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Existing plaques and neuritic abnormalities in APP:PS1 mice are not affected by administration of the gamma-secretase inhibitor LY-411575..
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2009
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"What kills neurons in neurodegenerative diseases?", a review series in an open access journal..
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2009
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The therapeutic importance of understanding mechanisms of neuronal cell death in neurodegenerative disease..
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2009
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Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivo..
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2009
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Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Abeta levels..
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2007
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Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms..
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2007
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Signal peptide peptidase (SPP) dimer formation as assessed by fluorescence lifetime imaging microscopy (FLIM) in intact cells..
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2006
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Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel gamma-secretase substrates..
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2006
Identity
International Standard Serial Number (ISSN)