Selected Publications
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article
- Targeting cellular senescence in metabolic disease.. Molecular metabolism. -. 2022
- Metabolic changes in aging humans: current evidence and therapeutic strategies.. The Journal of clinical investigation. 132. 2022
- Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans.. EBioMedicine. -. 2022
- Senolytics: Potential for Alleviating Diabetes and Its Complications.. Endocrinology. 162. 2021
- 17α-Estradiol Modulates IGF1 and Hepatic Gene Expression in a Sex-Specific Manner.. The journals of gerontology. Series A, Biological sciences and medical sciences. 76:778-785. 2021
- New Horizons: Novel Approaches to Enhance Healthspan Through Targeting Cellular Senescence and Related Aging Mechanisms.. The Journal of clinical endocrinology and metabolism. 106:e1481-e1487. 2021
- Senescence marker activin A is increased in human diabetic kidney disease: association with kidney function and potential implications for therapy.. BMJ open diabetes research & care. 7:-. 2019
- Cellular senescence: at the nexus between ageing and diabetes.. Diabetologia. 62:1835-1841. 2019
- Targeting senescent cells alleviates obesity-induced metabolic dysfunction.. Aging cell. 18:-. 2019
- Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.. Cell metabolism. 29:1061-1077.e8. 2019
- Senolytics improve physical function and increase lifespan in old age.. Nature medicine. 24:1246-1256. 2018
- Cellular senescence drives age-dependent hepatic steatosis.. Nature communications. -. 2017
- Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.. Aging cell. 15:973-7. 2016
- Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.. Diabetes. 65:1606-15. 2016
- Aging and adipose tissue: potential interventions for diabetes and regenerative medicine.. Experimental gerontology. 97-105. 2016
- 17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.. The journals of gerontology. Series A, Biological sciences and medical sciences. 72:3-15. 2016
- Targeting senescent cells enhances adipogenesis and metabolic function in old age.. eLife. -. 2015
- Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.. Diabetes. 64:2289-98. 2015
- The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.. Aging cell. 14:644-58. 2015
- Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.. Aging. 6:575-86. 2014
- Human papillomavirus vaccination: a case study in translational science.. Clinical and translational science. 7:420-4. 2014