Selected Publications
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article
- The Inflammasome Adaptor Protein ASC in Plasma as a Biomarker of Early Cognitive Changes.. International journal of molecular sciences. 25. 2024
- Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease.. Neural regeneration research. 20:1644-1664. 2024
- Extracellular Vesicle ASC: A Novel Mediator for Lung-Brain Axis in Preterm Brain Injury.. American journal of respiratory cell and molecular biology. 2024
- Increased inflammasome protein expression identified in microglia from postmortem brains with schizophrenia.. Journal of neuropathology and experimental neurology. 2024
- IC100, a humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice.. Angiogenesis. 27:423-440. 2024
- Extracellular vesicles mediate inflammasome signaling in the brain and heart of Alzheimer's disease mice.. Frontiers in molecular neuroscience. -. 2024
- post mortem. Alzheimer's & dementia (New York, N. Y.). 10:-. 2024
- The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes.. Cells. 12. 2023
- Prognostic and Diagnostic Utility of Serum Biomarkers in Pediatric Traumatic Brain Injury.. Journal of neurotrauma. 41:106-122. 2023
- Neural-Cardiac Inflammasome Axis after Traumatic Brain Injury.. Pharmaceuticals (Basel, Switzerland). 16. 2023
- Utility of Brain Injury Biomarkers in Children With Congenital Heart Disease Undergoing Cardiac Surgery.. Pediatric neurology. 44-53. 2023
- Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson's Disease.. Pharmaceuticals (Basel, Switzerland). 16. 2023
- Sex Differences in the Inflammatory Profile in the Brain of Young and Aged Mice.. Cells. 12. 2023
- Importance of timing optimization for closed-loop applications of vagus nerve stimulation.. Bioelectronic medicine. 9:-. 2023
- Inflammasome signaling proteins as biomarkers of COVID-19.. Frontiers in immunology. -. 2023
- Activation of inflammasomes and their effects on neuroinflammation at the microelectrode-tissue interface in intracortical implants.. Biomaterials. -. 2023
- Genetic Predisposition to Alzheimer's Disease Alters Inflammasome Activity After Traumatic Brain Injury.. Translational research : the journal of laboratory and clinical medicine. 66-77. 2023
- Methods to Study Inflammasome Activation in the Central Nervous System: Immunoblotting and Immunohistochemistry.. Methods in molecular biology (Clifton, N.J.). 223-238. 2023
- Identification of inflammasome signaling proteins in neurons and microglia in early and intermediate stages of Alzheimer's disease.. Brain pathology (Zurich, Switzerland). 33:-. 2022
- Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview.. Neuroscience and biobehavioral reviews. -. 2022
- Intraocular inflammasome signalling in failed corneal transplants.. Eye (London, England). 37:787-789. 2022
- Inflammasome activation in traumatic brain injury and Alzheimer's disease.. Translational research : the journal of laboratory and clinical medicine. 1-12. 2022
- The inflammasome pathway: A key player in ocular surface and anterior segment diseases.. Survey of ophthalmology. 68:280-289. 2022
- MECHANISM OF ACTION OF IC 100, A HUMANIZED IgG4 MONOCLONAL ANTIBODY TARGETING APOPTOSIS-ASSOCIATED SPECK-LIKE STAINING PROTEIN CONTAINING A CASPASE RECRUITMENT DOMAIN (ASC).. Translational research : the journal of laboratory and clinical medicine. 27-40. 2022
- Cohort study on the differential expression of inflammatory and angiogenic factors in thrombi, cerebral and peripheral plasma following acute large vessel occlusion stroke.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 42:-. 2022
- Inflammatory Biomarkers of Traumatic Brain Injury.. Pharmaceuticals (Basel, Switzerland). 15. 2022
- Renal and Inflammatory Proteins as Biomarkers of Diabetic Kidney Disease and Lupus Nephritis.. Oxidative medicine and cellular longevity. -. 2022
- Role of Caspase-1 as a Biomarker of Ocular Surface Damage.. American journal of ophthalmology. 74-83. 2022
- The Role of Non-canonical and Canonical Inflammasomes in Inflammaging.. Frontiers in molecular neuroscience. -. 2022
- Serum Caspase-1 as an Independent Prognostic Factor in Traumatic Brain Injured Patients.. Neurocritical care. 36:527-535. 2021
- Age-Dependent Microglial Response to Systemic Infection.. Cells. 10. 2021
- Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats.. Scientific reports. 11:-. 2021
- Tumor necrosis factor-alpha and interferon-gamma induce inflammasome-mediated corneal endothelial cell death.. Experimental eye research. -. 2021
- Netosis and Inflammasomes in Large Vessel Occlusion Thrombi.. Frontiers in pharmacology. -. 2021
- Inflammasome Proteins as Inflammatory Biomarkers of Age-Related Macular Degeneration.. Translational vision science & technology. 9:-. 2020
- Inflammasome Proteins as Inflammatory Biomarkers of Age-Related Macular Degeneration.. Translational vision science & technology. 9:-. 2020
- ASC, IL-18 and Galectin-3 as Biomarkers of Non-Alcoholic Steatohepatitis: A Proof of Concept Study.. International journal of molecular sciences. 21. 2020
- The Inflammasome in Times of COVID-19.. Frontiers in immunology. -. 2020
- The Inflammasome in Times of COVID-19.. Frontiers in immunology. -. 2020
- Role of inflammasomes in multiple sclerosis and their potential as therapeutic targets.. Journal of neuroinflammation. 17:-. 2020
- Enoxaparin Attenuates Acute Lung Injury and Inflammasome Activation after Traumatic Brain Injury.. Journal of neurotrauma. 38:646-654. 2020
- The Inflammasome Signaling Proteins ASC and IL-18 as Biomarkers of Psoriasis.. Frontiers in pharmacology. -. 2020
- The Inflammasome Adaptor Protein ASC in Mild Cognitive Impairment and Alzheimer's Disease.. International journal of molecular sciences. 21. 2020
- IC100: a novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis.. Journal of neuroinflammation. 17:-. 2020
- Levels of caspase-1 in cerebrospinal fluid of patients with traumatic brain injury: correlation with intracranial pressure and outcome.. Journal of neurosurgery. 134:1644-1649. 2020
- The Inflammasome in Reproductive Biology: A Promising Target for Novel Therapies.. Frontiers in endocrinology. -. 2020
- Oligodendrocytes modulate the immune-inflammatory response in EAE via TNFR2 signaling.. Brain, behavior, and immunity. 132-146. 2019
- Neural-respiratory inflammasome axis in traumatic brain injury.. Experimental neurology. -. 2019
- Caspase-1 Inhibition Attenuates Hyperoxia-induced Lung and Brain Injury in Neonatal Mice.. American journal of respiratory cell and molecular biology. 61:341-354. 2019
- Estrogen preconditioning: A promising strategy to reduce inflammation in the ischemic brain.. Conditioning medicine. 2:106-113. 2019
- The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury.. Journal of neuroinflammation. 16:-. 2019
- Human Lung Cell Pyroptosis Following Traumatic Brain Injury.. Cells. 8. 2019
- Carbon monoxide releasing molecule-3 inhibits inflammasome activation: A potential therapy for spinal cord injury.. EBioMedicine. 17-18. 2019
- Inflammasome proteins as biomarkers of traumatic brain injury.. PloS one. 13:-. 2018
- Sexual dimorphism in inflammasome-containing extracellular vesicles and the regulation of innate immunity in the brain of reproductive senescent females.. Neurochemistry international. 29-37. 2018
- Contribution of the inflammasome to inflammaging.. Journal of inflammation (London, England). -. 2018
- Inflammasome Proteins in Serum and Serum-Derived Extracellular Vesicles as Biomarkers of Stroke.. Frontiers in molecular neuroscience. -. 2018
- Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response.. Neuron. 99:914-924.e3. 2018
- Traumatic Brain Injury-Induced Acute Lung Injury: Evidence for Activation and Inhibition of a Neural-Respiratory-Inflammasome Axis.. Journal of neurotrauma. 35:2067-2076. 2018
- Nicotine Alters Estrogen Receptor-Beta-Regulated Inflammasome Activity and Exacerbates Ischemic Brain Damage in Female Rats.. International journal of molecular sciences. 19. 2018
- Microglial Inflammasome Activation in Penetrating Ballistic-Like Brain Injury.. Journal of neurotrauma. 35:1681-1693. 2018
- Inflammasome Proteins As Biomarkers of Multiple Sclerosis.. Frontiers in neurology. -. 2018
- Inhibition of Rac1 Signaling Downregulates Inflammasome Activation and Attenuates Lung Injury in Neonatal Rats Exposed to Hyperoxia.. Neonatology. 111:280-288. 2016
- A computational model for investigating the effects of changes in bioavailability of insulin-like growth factor-1 on the homeostasis of the intervertebral disc.. Computers in biology and medicine. 126-137. 2016
- Acidification changes affect the inflammasome in human nucleus pulposus cells.. Journal of inflammation (London, England). 13:-. 2016
- Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice.. The Journal of experimental medicine. 213:929-49. 2016
- Estrogen receptor beta signaling alters cellular inflammasomes activity after global cerebral ischemia in reproductively senescence female rats.. Journal of neurochemistry. 136:492-6. 2015
- RIG-I contributes to the innate immune response after cerebral ischemia.. Journal of inflammation (London, England). -. 2015
- RIG-I contributes to the innate immune response after cerebral ischemia.. Journal of inflammation (London, England). -. 2015
- Effects of Tobacco Smoking on the Degeneration of the Intervertebral Disc: A Finite Element Study.. PloS one. 10:-. 2015
- Therapeutics targeting the inflammasome after central nervous system injury.. Translational research : the journal of laboratory and clinical medicine. 167:35-45. 2015
- Exosome-mediated inflammasome signaling after central nervous system injury.. Journal of neurochemistry. 136 Suppl 1:39-48. 2015
- Mincle signaling in the innate immune response after traumatic brain injury.. Journal of neurotrauma. 32:228-36. 2014
- Mincle signaling in the innate immune response after traumatic brain injury.. Journal of neurotrauma. 32:228-36. 2014
- A computational analysis on the implications of age-related changes in the expression of cellular signals on the role of IGF-1 in intervertebral disc homeostasis.. Journal of biomechanics. 48:332-9. 2014
- Neutralization of ASC improves sperm motility in men with spinal cord injury.. Human reproduction (Oxford, England). 29:2368-73. 2014
- Pattern recognition receptors and central nervous system repair.. Experimental neurology. 5-16. 2014
- The inflammasome pyrin contributes to pertussis toxin-induced IL-1β synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis.. PLoS pathogens. 10:-. 2014
- RIG-1 receptor expression in the pathology of Alzheimer's disease.. Journal of neuroinflammation. -. 2014
- Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 34:369-75. 2014
- Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 34:621-9. 2014
- Deep tissue injury in development of pressure ulcers: a decrease of inflammasome activation and changes in human skin morphology in response to aging and mechanical load.. PloS one. 8:-. 2013
- Human astrocytes express a novel NLRP2 inflammasome.. Glia. 61:1113-21. 2013
- Inflammasome proteins in cerebrospinal fluid of brain-injured patients as biomarkers of functional outcome: clinical article.. Journal of neurosurgery. 117:1119-25. 2012
- Involvement of the inflammasome in abnormal semen quality of men with spinal cord injury.. Fertility and sterility. 99:118-124.e2. 2012
- Effects of therapeutic hypothermia on inflammasome signaling after traumatic brain injury.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 32:1939-47. 2012
- Caspase-1 level is higher in the scalp in androgenetic alopecia.. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 38:1033-9. 2012
- P2X4 receptors influence inflammasome activation after spinal cord injury.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32:3058-66. 2012
- Astrogliosis involves activation of retinoic acid-inducible gene-like signaling in the innate immune response after spinal cord injury.. Glia. 60:414-21. 2011
- Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats.. BMC neuroscience. -. 2011
- Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain.. Brain research. 23-34. 2011
- In vivo electroporation and non-protein based screening assays to identify antibodies against native protein conformations.. Hybridoma (2005). 30:409-18. 2011
- Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury.. Journal of neurotrauma. 29:936-45. 2011
- Functional recovery after peripheral nerve injury is dependent on the pro-inflammatory cytokines IL-1β and TNF: implications for neuropathic pain.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31:12533-42. 2011
- Oligodendrocyte vulnerability following traumatic brain injury in rats.. Neuroscience letters. 499:143-8. 2011
- Oligodendrocyte vulnerability following traumatic brain injury in rats.. Neuroscience letters. 499:143-8. 2011
- OLIGODENDROCYTE VULNERABILITY FOLLOWING TRAUMATIC BRAIN INJURY IN RATS: EFFECT OF MODERATE HYPOTHERMIA.. Therapeutic hypothermia and temperature management. 1:43-51. 2011
- Neuroprotective effects of bone morphogenetic protein 7 (BMP7) treatment after spinal cord injury.. Neuroscience letters. 465:226-9. 2009
- Alterations in blood-brain barrier permeability to large and small molecules and leukocyte accumulation after traumatic brain injury: effects of post-traumatic hypothermia.. Journal of neurotrauma. 26:1123-34. 2009
- The pannexin 1 channel activates the inflammasome in neurons and astrocytes.. The Journal of biological chemistry. 284:18143-51. 2009
- Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 29:1251-61. 2009
- Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 29:534-44. 2008
- A molecular platform in neurons regulates inflammation after spinal cord injury.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28:3404-14. 2008
- Therapeutic hypothermia modulates TNFR1 signaling in the traumatized brain via early transient activation of the JNK pathway and suppression of XIAP cleavage.. The European journal of neuroscience. 24:2283-90. 2006