Selected Publications article Personalized and muscle-specific OXPHOS measurement with integrated CrCEST MRI and proton MR spectroscopy.. Nature communications. 15:-. 2024 Double malnutrition and associated factors in a middle-aged and older, rural South African population.. BMC nutrition. 10:-. 2024 Improving Medical Communication-Reply.. JAMA. 331:-. 2024 Misinformation and the Vaccine Adverse Event Reporting System.. JAMA. 331:1005-1006. 2024 Communicating Medicine-A New JAMA Series.. JAMA. 331:-. 2024 Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.. Nature communications. 15:-. 2024 Using Natural Language Processing to Extract and Classify Symptoms Among Patients with Thyroid Dysfunction.. Studies in health technology and informatics. 614-618. 2024 Association of thyroid dysfunction in individuals ≥ 65 years of age with subclinical cardiac abnormalities.. The Journal of clinical endocrinology and metabolism. 2024 Strategies to Improve Medical Communication.. JAMA. 331:70-71. 2024 The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis.. The lancet. Diabetes & endocrinology. 11:743-754. 2023 Hormones and Aging: An Endocrine Society Scientific Statement.. The Journal of clinical endocrinology and metabolism. 108:1835-1874. 2023 Barriers to and solutions for representative inclusion across the lifespan and in life course research: The need for structural competency highlighted by the COVID-19 pandemic.. Journal of clinical and translational science. 7:-. 2022 Subclinical thyroid dysfunction and incident diabetes: a systematic review and an individual participant data analysis of prospective cohort studies.. European journal of endocrinology. 187:S35-S46. 2022 Changes in the Hierarchy of Functional Impairment From Middle Age to Older Age.. The journals of gerontology. Series A, Biological sciences and medical sciences. 77:1577-1584. 2022 Sex Differences in Recovery Across Multiple Domains Among Older Adults With Hip Fracture.. The journals of gerontology. Series A, Biological sciences and medical sciences. 77:1463-1471. 2022 Addressing Online Health Privacy Risks for Older Adults: A Perspective on Ethical Considerations and Recommendations.. Gerontology & geriatric medicine. -. 2022 Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies.. Frontiers in psychiatry. -. 2022 Challenges in the Management of Atrial Fibrillation With Subclinical Hyperthyroidism.. Frontiers in endocrinology. -. 2022 Subclinical hypothyroidism in older individuals.. The lancet. Diabetes & endocrinology. 10:129-141. 2021 Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer.. Nature communications. 12:-. 2021 Osteoporosis, Rather Than Sarcopenia, Is the Predominant Musculoskeletal Disease in a Rural South African Community Where Human Immunodeficiency Virus Prevalence Is High: A Cross-Sectional Study.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 37:244-255. 2021 Association of Thyroid Dysfunction With Cognitive Function: An Individual Participant Data Analysis.. JAMA internal medicine. 181:1440-1450. 2021 Evaluation and disposition of older adults presenting to the emergency department with abdominal pain.. Journal of the American Geriatrics Society. 70:501-511. 2021 Sex-specific 25-hydroxyvitamin D threshold concentrations for functional outcomes in older adults: PRoject on Optimal VItamin D in Older adults (PROVIDO).. The American journal of clinical nutrition. 114:16-28. 2021 Autoimmune Thyroid Disease in Women.. JAMA. 325:2392-2393. 2021 Effect of Targeted Messaging on Return to In-Person Visits During the COVID-19 Pandemic: A Randomized Clinical Trial.. JAMA network open. 4:-. 2021 Cortisol and Dehydroepiandrosterone Response to Adrenocorticotropic Hormone and Frailty in Older Women.. The journals of gerontology. Series A, Biological sciences and medical sciences. 76:901-905. 2021 The USPSTF 2021 Recommendations on Screening for Asymptomatic Vitamin D Deficiency in Adults: The Challenge for Clinicians Continues.. JAMA. 325:1401-1402. 2021 Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document.. European thyroid journal. 10:10-38. 2021 Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document.. Thyroid : official journal of the American Thyroid Association. 31:156-182. 2021 An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms.. Scientific reports. 10:-. 2020 GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.. Nature communications. 11:-. 2020 Letter to the Editor: "Our Response to COVID-19 as Endocrinologists and Diabetologists".. The Journal of clinical endocrinology and metabolism. 105. 2020 Editorial: Combination Therapy for Hypothyroidism: The Journey From Bench to Bedside.. Frontiers in endocrinology. -. 2020 Continuous Glucose Monitoring in Adolescent, Young Adult, and Older Patients With Type 1 Diabetes.. JAMA. 323:2384-2385. 2020 Design of the Optimal Trial of Combination Therapy.. Frontiers in endocrinology. -. 2020 The Thyrotropin Reference Range Should Be Changed in Older Patients.. JAMA. 322:1961-1962. 2019 Patient Context and Thyrotropin Levels Are Important When Considering Treatment of Subclinical Hypothyroidism.. Thyroid : official journal of the American Thyroid Association. 29:1359-1363. 2019 Thyroid Function Test Abnormalities During Pregnancy.. JAMA. 322:617-619. 2019 Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies.. BMJ open. 9:-. 2019 Subclinical Hypothyroidism: A Review.. JAMA. 322:153-160. 2019 Thyroid and Cardiovascular Disease Research Agenda for Enhancing Knowledge, Prevention, and Treatment.. Circulation. 139:2892-2909. 2019 Thyroid and Cardiovascular Disease: Research Agenda for Enhancing Knowledge, Prevention, and Treatment.. Thyroid : official journal of the American Thyroid Association. 29:760-777. 2019 Low thyroid function is not associated with an accelerated deterioration in renal function.. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 34:650-659. 2019 Response by Cappola and Cappola to Letter Regarding Article, "Thyroid Dysfunction in Heart Failure and Cardiovascular Outcomes".. Circulation. Heart failure. 12:-. 2019 Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study.. JAMA cardiology. 4:144-152. 2019 Association of Biomarker and Physiologic Indices With Mortality in Older Adults: Cardiovascular Health Study.. The journals of gerontology. Series A, Biological sciences and medical sciences. 74:114-120. 2019 Thyroid Dysfunction in Heart Failure and Cardiovascular Outcomes.. Circulation. Heart failure. 11:-. 2018 Taste Perception and Water Swallow Screen Results in Old-Old Women.. Geriatrics (Basel, Switzerland). 3. 2018 Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.. Nature communications. 9:-. 2018 The Relation Between Thyroid Function and Anemia: A Pooled Analysis of Individual Participant Data.. The Journal of clinical endocrinology and metabolism. 103:3658-3667. 2018 Clinical aspects of thyroid function during ageing.. The lancet. Diabetes & endocrinology. 6:733-742. 2018 Trajectories of IGF-I Predict Mortality in Older Adults: The Cardiovascular Health Study.. The journals of gerontology. Series A, Biological sciences and medical sciences. 73:953-959. 2018 Diagnostic Accuracy of Ultrasound With Color Flow Doppler in Children With Thyroid Nodules.. The Journal of clinical endocrinology and metabolism. 103:1958-1965. 2018 An Online Survey of Hypothyroid Patients Demonstrates Prominent Dissatisfaction.. Thyroid : official journal of the American Thyroid Association. 28:707-721. 2018 The Association Between IGF-I and IGFBP-3 and Incident Diabetes in an Older Population of Men and Women in the Cardiovascular Health Study.. The Journal of clinical endocrinology and metabolism. 102:4541-4547. 2017 Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation.. Circulation. 136:2100-2116. 2017 Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease.. The Journal of clinical endocrinology and metabolism. 102:2853-2861. 2017 Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts.. The Journal of clinical endocrinology and metabolism. 102:2719-2728. 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.. PLoS genetics. 13:-. 2017 How to Look for Thyroid Cancer.. JAMA. 317:1840-1841. 2017 Response to the Letter by Choy.. The Journal of clinical endocrinology and metabolism. 102:1409-1410. 2017 Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study.. Alzheimer disease and associated disorders. 31:107-113. 2017 Insulinlike Growth Factor Binding Protein-1 and Ghrelin Predict Health Outcomes Among Older Adults: Cardiovascular Health Study Cohort.. The Journal of clinical endocrinology and metabolism. 102:267-278. 2017 Thyroid-Stimulating Hormone in the Evaluation of Subclinical Hypothyroidism.. JAMA. 316:1592-1593. 2016 Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis.. The Journal of clinical endocrinology and metabolism. 101:4270-4282. 2016 Osteoporosis Therapy in Postmenopausal Women With High Risk of Fracture.. JAMA. 316:715-6. 2016 Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.. Aging cell. 15:811-24. 2016 Conflict or Confluence of Interest?--Reply.. JAMA. 315:1793-4. 2016 The Role of the Multiple Hormonal Dysregulation in the Onset of "Anemia of Aging": Focus on Testosterone, IGF-1, and Thyroid Hormones.. International journal of endocrinology. -. 2015 Confluence, Not Conflict of Interest: Name Change Necessary.. JAMA. 314:1791-2. 2015 Relationship between Carotenoids, Retinol, and Estradiol Levels in Older Women.. Nutrients. 7:6506-19. 2015 Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts.. JAMA internal medicine. 175:1037-47. 2015 Subclinical thyroid dysfunction and fracture risk: a meta-analysis.. JAMA. 313:2055-65. 2015 Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis.. The Journal of clinical endocrinology and metabolism. 100:2181-91. 2015 Improving the long-term management of benign thyroid nodules.. JAMA. 313:903-4. 2015 Thyroid function in the euthyroid range and adverse outcomes in older adults.. The Journal of clinical endocrinology and metabolism. 100:1088-96. 2014 Effects of transdermal testosterone treatment on inflammatory markers in elderly males.. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 20:1170-7. 2014 Levothyroxine prescription: not as simple as it seems.. JAMA. 311:2532-3. 2014 Controlling the metabolic roller coaster in diabetes.. JAMA. 311:2277-8. 2014 Thyroid antibody status, subclinical hypothyroidism, and the risk of coronary heart disease: an individual participant data analysis.. The Journal of clinical endocrinology and metabolism. 99:3353-62. 2014 Subclinical thyroid dysfunction and hip fracture and bone mineral density in older adults: the cardiovascular health study.. The Journal of clinical endocrinology and metabolism. 99:2657-64. 2014 Testosterone, dihydrotestosterone, and incident cardiovascular disease and mortality in the cardiovascular health study.. The Journal of clinical endocrinology and metabolism. 99:2061-8. 2014 Increasing use of vitamin D supplementation in the chronic renal insufficiency cohort study.. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 24:186-93. 2014 Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.. PLoS genetics. 10:-. 2014 Meta-analysis of loci associated with age at natural menopause in African-American women.. Human molecular genetics. 23:3327-42. 2014 Subclinical hypothyroidism, weight change, and body composition in the elderly: the Cardiovascular Health Study.. The Journal of clinical endocrinology and metabolism. 99:1220-6. 2014 Modeling Bivariate Longitudinal Hormone Profiles by Hierarchical State Space Models.. Journal of the American Statistical Association. 109:108-118. 2014 Testosterone therapy and risk of cardiovascular disease in men.. JAMA. 310:1805-6. 2013 Physical performance and frailty in chronic kidney disease.. American journal of nephrology. 38:307-15. 2013 Aging and endocrinology. Preface.. Endocrinology and metabolism clinics of North America. 42:xvii-xviii. 2013 Clinical review: The human experience with ghrelin administration.. The Journal of clinical endocrinology and metabolism. 98:1826-37. 2013 Persistent subclinical hypothyroidism and cardiovascular risk in the elderly: the cardiovascular health study.. The Journal of clinical endocrinology and metabolism. 98:533-40. 2012 Factors impacting the departure rates of female and male junior medical school faculty: evidence from a longitudinal analysis.. Journal of women's health (2002). 21:1059-65. 2012 Longitudinal changes in thyroid function in the oldest old and survival: the cardiovascular health study all-stars study.. The Journal of clinical endocrinology and metabolism. 97:3944-50. 2012 The natural history of subclinical hypothyroidism in the elderly: the cardiovascular health study.. The Journal of clinical endocrinology and metabolism. 97:1962-9. 2012 Integrated management of type 2 diabetes mellitus and depression treatment to improve medication adherence: a randomized controlled trial.. Annals of family medicine. 10:15-22. 2012 Dehydroepiandrosterone sulfate and postmenopausal women.. Current opinion in endocrinology, diabetes, and obesity. 18:171-6. 2011 Predictors of thyroid hormone initiation in older adults: results from the cardiovascular health study.. The journals of gerontology. Series A, Biological sciences and medical sciences. 66:809-14. 2011 Higher serum free testosterone concentration in older women is associated with greater bone mineral density, lean body mass, and total fat mass: the cardiovascular health study.. The Journal of clinical endocrinology and metabolism. 96:989-96. 2011 Effects of metformin and leuprolide acetate on insulin resistance and testosterone levels in nondiabetic postmenopausal women: a randomized, placebo-controlled trial.. Fertility and sterility. 94:2161-6. 2010 Cardiovascular disease is associated with greater incident dehydroepiandrosterone sulfate decline in the oldest old: the cardiovascular health study all stars study.. Journal of the American Geriatrics Society. 58:421-6. 2010 Higher serum testosterone concentration in older women is associated with insulin resistance, metabolic syndrome, and cardiovascular disease.. The Journal of clinical endocrinology and metabolism. 94:4776-84. 2009 Examining faculty awards for gender equity and evolving values.. Journal of general internal medicine. 25:57-60. 2009 Trajectories of dehydroepiandrosterone sulfate predict mortality in older adults: the cardiovascular health study.. The journals of gerontology. Series A, Biological sciences and medical sciences. 64:1268-74. 2009 Mindfulness Based Stress Reduction: effect on emotional distress in diabetes.. Practical diabetes international : the journal for diabetes care teams worldwide. 26:222-224. 2009 Multiple hormonal deficiencies in anabolic hormones are found in frail older women: the Women's Health and Aging studies.. The journals of gerontology. Series A, Biological sciences and medical sciences. 64:243-8. 2009 High frequency of and factors associated with thyroid hormone over-replacement and under-replacement in men and women aged 65 and over.. The Journal of clinical endocrinology and metabolism. 94:1342-5. 2009 Work-life policies for faculty at the top ten medical schools.. Journal of women's health (2002). 17:1311-20. 2008 The intersection of cancer and aging: establishing the need for breast cancer rehabilitation.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 16:866-72. 2007 Determinants of serum total and free testosterone levels in women over the age of 65 years.. The Journal of clinical endocrinology and metabolism. 92:509-16. 2006 DHEAS levels and mortality in disabled older women: the Women's Health and Aging Study I.. The journals of gerontology. Series A, Biological sciences and medical sciences. 61:957-62. 2006 Thyroid status, cardiovascular risk, and mortality in older adults.. JAMA. 295:1033-41. 2006 Insulin sensitizing pharmacotherapy for prevention of myocardial infarction in patients with diabetes mellitus.. The American journal of cardiology. 97:651-4. 2006 Hypothyroidism and atherosclerosis.. The Journal of clinical endocrinology and metabolism. 88:2438-44. 2003
Principal Investigator on Levothyroxine Dosing in Older Individuals 2023 - 2028 T4/T3 Therapy in Hypothyroidism 2024 - 2027 Diabetes, Endocrine, and Metabolism 1978 - 2026 Midcareer Investigator Award in Patient-Oriented Research in Aging 2013 - 2025 Developing Oral LT3 Therapy for Heart Failure 2019 - 2024 Diabetes, Endocrine and Metabolic Disease 1978 - 2021 Diabetes, Endocrine, and Metabolic Disease 1978 - 2016 Ghrelin and Strength Training in Frail Elderly 2011 - 2014 Subclinical thyroid dysfunction in the elderly 2009 - 2014 Hormonal trajectories in aging 2006 - 2012 Androgens, Myostatin, and Sarcopenia in Older Women 2002 - 2007
Available to Provide Advice to Those At different institutions (mentor and mentee are at different institutions) At my institution (mentor and mentee at same institution but different research interests or departments) From different disciplines or subspecialties
Available to be Contacted for Career (e.g. networking, how to get grants, how to publish, how to get tenure, how to start a geriatric specialty clinic) Research (e.g. reviewing study design, specific aims, selecting instruments) Work/Life Balance (e.g. counseling on job stress, dual-career households, self-care)