Publications in VIVO

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Co-investigator Network

Brian J Andonian, MD, MHSc

Person

Positions

Assistant Professor, Duke University School of Medicine

I am a rheumatologist and clinician scientist studying the effects of exercise training and lifestyle interventions on immune cell aging, metabolic health, and molecular function in persons with rheumatoid arthritis (RA). The goal of my translational research is to improve outcomes in patients with chronic inflammatory diseases of aging such as RA, including disease activity, cardiometabolic risk, and disability, via personalized lifestyle and pharmacologic prescription.

Clinical Disciplines

GEMSSTAR awardee

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Selected Publications

article
1. Inflammation and aging-related disease: A transdisciplinary inflammaging framework.. GeroScience. 2024
2. Effect of Remotely Supervised Weight Loss and Exercise Training Versus Lifestyle Counseling on Cardiovascular Risk and Clinical Outcomes in Older Adults With Rheumatoid Arthritis: A Randomized Controlled Trial.. ACR open rheumatology. 6:124-136. 2023
3. Remotely Supervised Weight Loss and Exercise Training to Improve Rheumatoid Arthritis Cardiovascular Risk: Rationale and Design of the Supervised Weight Loss Plus Exercise Training-Rheumatoid Arthritis Trial.. ACR open rheumatology. 2023
4. Rheumatoid arthritis T cell and muscle oxidative metabolism associate with exercise-induced changes in cardiorespiratory fitness.. Scientific reports. 12:-. 2022
5. Using Machine Learning to Identify Organ System Specific Limitations to Exercise via Cardiopulmonary Exercise Testing. IEEE Journal of Biomedical and Health Informatics. 2022
6. Potential insights into the role of biomechanical stress in axial spondyloarthritis from idiopathic hypoparathyroidism, a rare disease with intriguing skeletal manifestations.. Clinical and experimental rheumatology. 39:1269-1271. 2021
7. Making Cardiopulmonary Exercise Testing Interpretable for Clinicians.. Current sports medicine reports. 20:545-552. 2021
8. Altered skeletal muscle metabolic pathways, age, systemic inflammation, and low cardiorespiratory fitness associate with improvements in disease activity following high-intensity interval training in persons with rheumatoid arthritis.. Arthritis research & therapy. 23:-. 2021
9. Exercise protects against cardiac and skeletal muscle dysfunction in a mouse model of inflammatory arthritis.. Journal of applied physiology (Bethesda, Md. : 1985). 130:853-864. 2021
10. Biomechanical Factors May Be the Main Contributor to Entheseal Changes in Normal Adults.. The Journal of rheumatology. 2021
11. Making Cardiopulmonary Exercise Testing Interpretable for Clinicians.. Current Sports Medicine Reports. 2021
12. Skeletal muscle disease in rheumatoid arthritis: the center of cardiometabolic comorbidities?. Current opinion in rheumatology. 32:297-306. 2020
13. Benefits and promotion of physical activity in rheumatoid arthritis.. Current opinion in rheumatology. 2020
14. Skeletal muscle disease in rheumatoid arthritis: the center of cardiometabolic comorbidities?. Current opinion in rheumatology. 2020
15. Plasma MicroRNAs in Established Rheumatoid Arthritis Relate to Adiposity and Altered Plasma and Skeletal Muscle Cytokine and Metabolic Profiles.. Frontiers in immunology. -. 2019
16. Trends in cardiorespiratory fitness: The evolution of exercise treadmill testing at a single Academic Medical Center from 1970 to 2012.. American heart journal. 88-97. 2019
17. Effect of high-intensity interval training on muscle remodeling in rheumatoid arthritis compared to prediabetes.. Arthritis research & therapy. 20:-. 2018
18. Molecular alterations in skeletal muscle in rheumatoid arthritis are related to disease activity, physical inactivity, and disability.. Arthritis research & therapy. 19:-. 2017
19. Autoimmune meningoencephalitis in a melanoma patient treated with ipilimumab.. Immunotherapy. 2016
20. Stiffness of resting lumbar myofascia in healthy young subjects quantified using a handheld myotonometer and concurrently with surface electromyography monitoring.. Journal of Bodywork and Movement Therapies. 2016
21. Greater Resting Lumbar Extensor Myofascial Stiffness in Younger Ankylosing Spondylitis Patients Than Age-Comparable Healthy Volunteers Quantified by Myotonometry.. Archives of physical medicine and rehabilitation. 2015
22. Mechanobiology likely contributes to immunobiology pathways in the pathogenesis of ankylosing spondylitis.. Clinical and experimental rheumatology. 2012
23. Mechanobiology likely contributes to immunobiology pathways in the pathogenesis of ankylosing spondyltitis.. Clinical and experimental rheumatology. 2012
24. Integrative structural biomechanical concepts of ankylosing spondylitis.. Arthritis. 2011
document
1. Forearm Muscle Oxidative Capacity And Biomechanical Property Testing As Clinical Tools For Rheumatoid Arthritis. Medicine and science in sports and exercise. 2022
2. A Challenging Case of Endocarditis-Multi-Disciplinary Approach is an Achievable Chimera. Circulation. 2021
3. A Simplified And Intuitive Visualization For Cardiopulmonary Exercise Testing Data. Medicine and science in sports and exercise. 2021
4. Altered Skeletal Muscle Metabolic Pathways, Age, Systemic Inflammation, and Low Cardiorespiratory Fitness Associate with Improvements in Disease Activity Following High-Intensity Interval Training in Persons with Rheumatoid Arthritis 2021
5. EFFECT OF HIGH-INTENSITY INTERVAL TRAINING ON RHEUMATOID ARTHRITIS CD4+T CELL OXIDATIVE METABOLISM. Innovation in Aging. 2021
6. High-Intensity Interval Training Increases Rheumatoid Arthritis Cardiorespiratory Fitness in Association with Improvements in CD4+T Cell and Skeletal Muscle Mitochondrial Metabolism. Arthritis and Rheumatology. 2020
7. Skeletal Muscle Metabolic Gene Profile Associates With Rheumatoid Arthritis Improvements Following High Intensity Interval Training. Medicine and science in sports and exercise. 2020
8. A Quality Improvement Project to Increase Documentation Efficiency in an Academic Rheumatology Practice. Arthritis and Rheumatology. 2019
9. High Intensity Interval Training Improves Rheumatoid Arthritis Cardiorespiratory Fitness and Systemic Inflammation in Association with Alterations in Skeletal Muscle Metabolomic Profiles. Arthritis and Rheumatology. 2019
10. A Quality Improvement Initiative to Increase Adherence to Hydroxychloroquine Dosing Guidelines at an Academic Medical Center. Arthritis and Rheumatology. 2018
11. Plasma Mir-146a-5p Associates with Beneficial Body Composition and Plasma Metabolic Profiles in Rheumatoid Arthritis. Arthritis and Rheumatology. 2018
12. Serum Galectin-3 in Rheumatoid Arthritis Compared with Healthy Controls and Subjects with Prediabetes before and after High-Intensity Interval Training. Arthritis and Rheumatology. 2017
13. Skeletal Muscle Cytokine and Myostatin Responses to High-Intensity Interval Training in Rheumatoid Arthritis Contrasted with Prediabetes Mellitus. Arthritis and Rheumatology. 2017