Publications in VIVO

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Co-investigator Network

Breno Diniz

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Associate Professor, University of Connecticut Health Center

Clinical Disciplines

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Selected Publications

article
1. Cognitive Frailty is Associated With Elevated Proinflammatory Markers and a Higher Risk of Mortality.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 30:825-833. 2022
2. Association of Molecular Senescence Markers in Late-Life Depression With Clinical Characteristics and Treatment Outcome. 2022
3. Higher IL-6 and IL-4 plasma levels in depressed elderly women are influenced by diabetes mellitus.. Trends in psychiatry and psychotherapy. 44. 2022
4. Increased Levels of Circulating Cell-Free mtDNA in the Plasma of Subjects With Late-Life Depression and Frailty: A Preliminary Study.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 30:332-337. 2021
5. Editorial: Cognitive Impairment and Inflammation in Old Age and the Role of Modifiable Risk Factors of Neurocognitive Disorders. 2021
6. Mild cognitive impairment and major depressive disorder are associated with molecular senescence abnormalities in older adults. 2021
7. Oxidative DNA damage is increased in older adults with a major depressive episode: A preliminary study.. Journal of Affective Disorders. 279:106-110. 2021
8. APOE ε4 and the Influence of Sex, Age, Vascular Risk Factors, and Ethnicity on Cognitive Decline.. The journals of gerontology. Series A, Biological sciences and medical sciences. 75:1863-1873. 2020
9. Biomarkers intersection between depression, diabetes, and cognitive impairment.. International psychogeriatrics. 32:5-6. 2020
10. Education and the moderating roles of age, sex, ethnicity and apolipoprotein epsilon 4 on the risk of cognitive impairment.. Archives of gerontology and geriatrics. 91:104112. 2020
11. Mild and moderate cognitive impairment and mortality among Brazilian older adults in long-term follow-up: The Bambui Health Aging Study.. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 42:583-590. 2020
12. Minocycline as adjunctive treatment for treatment-resistant depression: study protocol for a double blind, placebo-controlled, randomized trial (MINDEP2). 2020
13. Mood Disorders and Dementia: Time for Action.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 28:542-544. 2019
14. Diabetes, depressive symptoms, and mortality risk in old age: The role of inflammation.. Depression and anxiety. 36:941-949. 2019
15. Diet and Alzheimer's dementia - Nutritional approach to modulate inflammation.. Pharmacology, biochemistry, and behavior. 184:172743. 2019
16. Epidermal growth factor and fibroblast growth factor-2 circulating levels in elderly with major depressive disorder.. Psychiatry research. 272:141-143. 2019
17. Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults. 2019
18. Molecular Senescence Is Associated With White Matter Microstructural Damage in Late-Life Depression.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 27:1414-1418. 2019
19. The Gut Microbiome Alterations and Inflammation-Driven Pathogenesis of Alzheimer's Disease-a Critical Review.. Molecular neurobiology. 56:1841-1851. 2019
20. Depressive symptoms, emotional support and activities of daily living disability onset: 15-year follow-up of the Bambuí (Brazil) Cohort Study of Aging.. Cadernos de saude publica. 34:e00141917. 2018
21. Increased reward-oriented impulsivity in older bipolar patients: A preliminary study.. Journal of Affective Disorders. 225:585-592. 2018
22. Oxidative stress markers imbalance in late-life depression.. Journal of psychiatric research. 102:29-33. 2018
23. Plasma IL-17A levels in patients with late-life depression.. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 40:212-215. 2018
24. The association between systemic lupus erythematosus and dementia A meta-analysis.. Dementia & neuropsychologia. 12:143-151. 2018
25. The impact of substance use disorders on clinical outcomes in older-adult psychiatric inpatients.. International journal of geriatric psychiatry. 33:e323-e329. 2018
26. Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 14:280-292. 2017
27. Immunological biomarkers associated with brain structure and executive function in late-life depression: exploratory pilot study.. International journal of geriatric psychiatry. 32:692-699. 2017
28. Inflammatory Response in the CNS: Friend or Foe?. Molecular neurobiology. 54:8071-8089. 2017
29. Is It All about Inflammation?. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 25:1309-1310. 2017
30. What can BDNF genotype tell us about our memory?. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 39:87. 2017
31. The Vascular Impairment of Cognition Classification Consensus Study.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 13:624-633. 2016
32. Circulating biosignatures of late-life depression (LLD): Towards a comprehensive, data-driven approach to understanding LLD pathophysiology.. Journal of psychiatric research. 82:1-7. 2016
33. Components of the metabolic syndrome and depressive symptoms in community-dwelling older people: the Bambuí Cohort Aging Study.. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 38:183-9. 2016
34. Decreased Brain-Derived Neurotrophic Factor (BDNF) in Older Adults with Bipolar Disorder: Meaning and Utility?. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 24:602-603. 2016
35. Depressive symptoms increase the risk of progression to dementia in subjects with mild cognitive impairment: systematic review and meta-analysis.. International journal of geriatric psychiatry. 31:905-11. 2016
36. Insomnia and risk of dementia in older adults: Systematic review and meta-analysis.. Journal of psychiatric research. 77:109-15. 2016
37. Predictors and Moderators of Remission With Aripiprazole Augmentation in Treatment-Resistant Late-Life Depression: An Analysis of the IRL-GRey Randomized Clinical Trial. 2016
38. Shared Biologic Pathways Between Alzheimer Disease and Major Depression: A Systematic Review of MicroRNA Expression Studies.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 24:903-12. 2016
39. The Relationship between Sleep Complaints, Depression, and Executive Functions on Older Adults. 2016
40. Vascular depression consensus report - a critical update. 2016
41. Bipolar disorder prevalence: a systematic review and meta-analysis of the literature.. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 37:155-61. 2015
42. Cerebrospinal fluid biomarkers in Alzheimer's disease: Diagnostic accuracy and prediction of dementia. 2015
43. Decreased Neurotrophic Support is Associated with Cognitive Decline in Non-Demented Subjects.. Journal of Alzheimer's disease : JAD. 46:423-9. 2015
44. Lower Cerebrospinal Fluid Concentration of Brain-Derived Neurotrophic Factor Predicts Progression from Mild Cognitive Impairment to Alzheimer's Disease.. Neuromolecular medicine. 17:326-32. 2015
45. Plasma biosignature and brain pathology related to persistent cognitive impairment in late-life depression.. Molecular psychiatry. 20:594-601. 2015
46. Predictors of incidence of clinically significant depressive symptoms in the elderly: 10-year follow-up study of the Bambui cohort study of aging.. International journal of geriatric psychiatry. 30:1171-6. 2015
47. Regulation of leukocyte tricarboxylic acid cycle in drug-naïve Bipolar Disorder.. Neuroscience letters. 605:65-8. 2015
48. Specific cognitive functions and depressive symptoms as predictors of activities of daily living in older adults with heterogeneous cognitive backgrounds. 2015
49. Brain-derived neurotrophic factor levels in late-life depression and comorbid mild cognitive impairment: a longitudinal study.. Journal of psychiatric research. 49:96-101. 2014
50. Cognitive impairment in euthymic older adults with bipolar disorder: a controlled study using cognitive screening tests.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 22:389-97. 2014
51. Graph analysis of verbal fluency test discriminate between patients with Alzheimer's disease, mild cognitive impairment and normal elderly controls. 2014
52. Long-term lithium treatment reduces glucose metabolism in the cerebellum and hippocampus of nondemented older adults: an [¹⁸F]FDG-PET study. 2014
53. Major depressive disorder in older adults: benefits and hazards of prolonged treatment.. Drugs & aging. 31:661-9. 2014
54. Reduced cerebrospinal fluid levels of brain-derived neurotrophic factor is associated with cognitive impairment in late-life major depression.. The journals of gerontology. Series B, Psychological sciences and social sciences. 69:845-51. 2014
55. The effect of gender, age, and symptom severity in late-life depression on the risk of all-cause mortality: the Bambuí Cohort Study of Aging.. Depression and anxiety. 31:787-95. 2014
56. Clinical applicability and cutoff values for an unstructured neuropsychological assessment protocol for older adults with low formal education. 2013
57. Decreased levels of circulating adiponectin in mild cognitive impairment and Alzheimer's disease.. Neuromolecular medicine. 15:115-21. 2013
58. Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies.. The British journal of psychiatry : the journal of mental science. 202:329-35. 2013
59. Lithium and neuroprotection: translational evidence and implications for the treatment of neuropsychiatric disorders.. Neuropsychiatric disease and treatment. 9:493-500. 2013
60. Mild cognitive impairment. Part 1: clinical characteristics and predictors of dementia.. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 35:178-85. 2013
61. Mild cognitive impairment. Part 2: Biological markers for diagnosis and prediction of dementia in Alzheimer's disease.. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 35:284-94. 2013
62. Reduced serum nerve growth factor in patients with late-life depression.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 21:493-6. 2013
63. Alzheimer's disease.. Sub-cellular biochemistry. 65:329-52. 2012
64. Long-term sertraline treatment increases expression and decreases phosphorylation of glycogen synthase kinase-3B in platelets of patients with late-life major depression.. Journal of psychiatric research. 46:1053-8. 2012
65. Reduced platelet amyloid precursor protein ratio (APP ratio) predicts conversion from mild cognitive impairment to Alzheimer's disease.. Journal of neural transmission (Vienna, Austria : 1996). 119:815-9. 2012
66. Reduced serum levels of adiponectin in elderly patients with major depression.. Journal of psychiatric research. 46:1081-5. 2012
67. Brain-derived neurotrophic factor and Alzheimer's disease: physiopathology and beyond.. Neuromolecular medicine. 13:217-22. 2011
68. Current pharmacological approaches and perspectives in the treatment of geriatric mood disorders.. Current opinion in psychiatry. 24:473-7. 2011
69. Disease-modifying properties of long-term lithium treatment for amnestic mild cognitive impairment: randomised controlled trial.. The British journal of psychiatry : the journal of mental science. 198:351-6. 2011
70. Increased platelet GSK3B activity in patients with mild cognitive impairment and Alzheimer's disease.. Journal of psychiatric research. 45:220-4. 2011
71. Optimizing the CAMCOG test in the screening for mild cognitive impairment and incipient dementia: saving time with relevant domains.. International journal of geriatric psychiatry. 26:403-8. 2011
72. Platelet GSK3B activity in patients with late-life depression: marker of depressive episode severity and cognitive impairment?. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 12:216-22. 2011
73. Clinical and biological predictors of Alzheimer's disease in patients with amnestic mild cognitive impairment.. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 32:216-22. 2010
74. Cross-cultural adaptation, reliability and validity of the DAFS-R in a sample of Brazilian older adults.. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. 25:335-43. 2010
75. Diagnosis and biomarkers of predementia in Alzheimer's disease. 2010
76. Effect of brain-derived neurotrophic factor Val66Met polymorphism and serum levels on the progression of mild cognitive impairment.. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 11:774-80. 2010
77. Higher serum sTNFR1 level predicts conversion from mild cognitive impairment to Alzheimer's disease.. Journal of Alzheimer's disease : JAD. 22:1305-11. 2010
78. Increased soluble TNF receptor 2 in antidepressant-free patients with late-life depression.. Journal of psychiatric research. 44:917-20. 2010
79. Interleukin-1beta serum levels is increased in antidepressant-free elderly depressed patients.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 18:172-6. 2010
80. Serum brain-derived neurotrophic factor level is reduced in antidepressant-free patients with late-life depression.. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 11:550-5. 2010
81. Diagnostic transitions in mild cognitive impairment subtypes.. International psychogeriatrics. 21:1088-95. 2009
82. Increased serum IL-1beta level in Alzheimer's disease and mild cognitive impairment.. Dementia and geriatric cognitive disorders. 28:507-12. 2009
83. Neurobiological pathways to Alzheimer's disease: Amyloid-beta, TAU protein or both?. Dementia & neuropsychologia. 3:188-194. 2009
84. Neuropsychological profile of Brazilian older adults with heterogeneous educational backgrounds.. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. 24:71-9. 2009
85. Verbal fluency in the detection of mild cognitive impairment and Alzheimer's disease among Brazilian Portuguese speakers: the influence of education.. International psychogeriatrics. 21:1081-7. 2009
86. CAMcog as a screening tool for diagnosis of mild cognitive impairment and dementia in a Brazilian clinical sample of moderate to high education.. International journal of geriatric psychiatry. 23:1127-33. 2008
87. Combining functional scales and cognitive tests in screening for mild cognitive impairment at a university-based memory clinic in Brazil.. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 30:346-9. 2008
88. Do CSF total tau, phosphorylated tau, and beta-amyloid 42 help to predict progression of mild cognitive impairment to Alzheimer's disease? A systematic review and meta-analysis of the literature.. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 9:172-82. 2008
89. Mild cognitive impairment: cognitive screening or neuropsychological assessment?. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 30:316-21. 2008
90. Voxel-based morphometry in Alzheimer's disease.. Expert review of neurotherapeutics. 8:1691-702. 2008
91. [The use of antipsychotics in patients with dementia].. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 30:265-70. 2008
document
1. Trigeminal Nerve Stimulation (TNS) for Major Depressive Disorder in the Elderly: An Open Label Proof-of-Concept Trial.. Brain Stimulation. 146-7. 2016
review
1. The Molecular Intersection Between Senescence and Major Depression in the Elderly.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 1097-1105. 2018