Selected Publications
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article
- A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Posiphen in subjects with early Alzheimer's Disease.. Alzheimer's research & therapy. 16:-. 2024
- Longer Sleep Duration in Alzheimer's Disease Progression: A Compensatory Response?. Sleep. 47. 2024
- Propofol enhancement of slow wave sleep to target the nexus of geriatric depression and cognitive dysfunction: protocol for a phase I open label trial.. BMJ open. 14:-. 2024
- Sleep-wake body temperature regulates tau secretion in mice and correlates with CSF and plasma tau in humans.. Research square. 2024
- Evaluating a Novel 24-Hour Rest/Activity Rhythm Marker of Preclinical β-Amyloid Deposition.. Sleep. 47. 2024
- Response to Hypoglossal Nerve Stimulation Changes With Body Mass Index and Supine Sleep.. JAMA otolaryngology-- head & neck surgery. 150:421-428. 2024
- Midpoint of sleep is associated with sleep quality in older adults with and without symptomatic Alzheimer's disease.. Sleep advances : a journal of the Sleep Research Society. 5:-. 2024
- The CCJR® Gerard A. Engh Excellence in Knee Research Award: Remote Monitoring of Sleep Disturbance Following Total Knee Arthroplasty: A Cautionary Note.. The Journal of arthroplasty. 39:S22-S26. 2024
- Correction to: Role of sleep in neurodegeneration: the consensus report of the 5th Think Tank World Sleep Forum.. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 45:-. 2024
- A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Posiphen in subjects with Early Alzheimer's Disease.. medRxiv : the preprint server for health sciences. 2024
- Paradoxical effects of daytime sleepiness and memory in African Americans at risk for Alzheimer's disease.. Sleep. 47. 2024
- Role of sleep in neurodegeneration: the consensus report of the 5th Think Tank World Sleep Forum.. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 45:749-767. 2023
- Plasma and cerebrospinal fluid proteomic signatures of acutely sleep-deprived humans: an exploratory study.. Sleep advances : a journal of the Sleep Research Society. 4:-. 2023
- Mapping sleep's oscillatory events as a biomarker of Alzheimer's disease.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 20:301-315. 2023
- Reply to Suvorexant for Preventing Alzheimer's Disease.. Annals of neurology. 94:414-415. 2023
- Suvorexant Acutely Decreases Tau Phosphorylation and Aβ in the Human CNS.. Annals of neurology. 94:27-40. 2023
- Targeting Slow Wave Sleep Deficiency in Late-Life Depression: A Case Series With Propofol.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 31:643-652. 2023
- Sleep Disturbances Following Total Knee Arthroplasty.. The Journal of arthroplasty. 38:S120-S124. 2023
- Acute sleep loss decreases CSF-to-blood clearance of Alzheimer's disease biomarkers.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 19:3055-3064. 2023
- Age differences in the association between sleep and Alzheimer's disease biomarkers in the EPAD cohort.. Alzheimer's & dementia (Amsterdam, Netherlands). 14:-. 2022
- Around the EQUATOR with clinician-scientists transdisciplinary aging research (Clin-STAR) principles: Implementation science challenges and opportunities.. Journal of the American Geriatrics Society. 70:3620-3630. 2022
- Sleep Disturbances and Disorders in Patients with Knee Osteoarthritis and Total Knee Arthroplasty.. The Journal of bone and joint surgery. American volume. 104:1946-1955. 2022
- Moving Towards Core Sleep Outcomes in Neurodegenerative Disease - The Time Is Now.. Sleep. 45. 2022
- Adverse driving behaviors are associated with sleep apnea severity and age in cognitively normal older adults at risk for Alzheimer's disease.. Sleep. 45. 2022
- Importance of CSF-based Aβ clearance with age in humans increases with declining efficacy of blood-brain barrier/proteolytic pathways.. Communications biology. 5:-. 2022
- A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function.. Science advances. 7:-. 2021
- Sleep and longitudinal cognitive performance in preclinical and early symptomatic Alzheimer's disease.. Brain : a journal of neurology. 144:2852-2862. 2021
- Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panel.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 17:1528-1553. 2021
- Perioperative sleep in geriatric cardiac surgical patients: a feasibility study using a wireless wearable device.. British journal of anaesthesia. 126:e205-e208. 2021
- Closed-Loop Acoustic Stimulation During Sedation with Dexmedetomidine (CLASS-D): Protocol for a Within-Subject, Crossover, Controlled, Interventional Trial with Healthy Volunteers.. Nature and science of sleep. 303-313. 2021
- Protocol for the Prognosticating Delirium Recovery Outcomes Using Wakefulness and Sleep Electroencephalography (P-DROWS-E) study: a prospective observational study of delirium in elderly cardiac surgical patients.. BMJ open. 10:-. 2020
- Comparison of single-channel EEG, actigraphy, and sleep diary in cognitively normal and mildly impaired older adults.. Sleep advances : a journal of the Sleep Research Society. 1:-. 2020
- It's complicated: The relationship between sleep and Alzheimer's disease in humans.. Neurobiology of disease. -. 2020
- Diurnal Patterns for Cortisol, Cortisone and Agouti-Related Protein in Human Cerebrospinal Fluid and Blood.. The Journal of clinical endocrinology and metabolism. 105:e1584-92. 2020
- Sleep Deprivation Affects Tau Phosphorylation in Human Cerebrospinal Fluid.. Annals of neurology. 87:700-709. 2020
- Increased Cerebrospinal Fluid Amyloid-β During Sleep Deprivation in Healthy Middle-Aged Adults Is Not Due to Stress or Circadian Disruption.. Journal of Alzheimer's disease : JAD. 75:471-482. 2020
- SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases.. Nature reviews. Neurology. 15:419-427. 2019
- Multi-Modal Home Sleep Monitoring in Older Adults.. Journal of visualized experiments : JoVE. 2019
- The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans.. Science (New York, N.Y.). 363:880-884. 2019
- Reduced non-rapid eye movement sleep is associated with tau pathology in early Alzheimer's disease.. Science translational medicine. 11. 2019
- Reply to "Excess amyloid beta can be degraded in healthy humans".. Annals of neurology. 83:650-651. 2018
- Effect of sleep on overnight cerebrospinal fluid amyloid β kinetics.. Annals of neurology. 83:197-204. 2018
- Diurnal oscillation of CSF Aβ and other AD biomarkers.. Molecular neurodegeneration. 12:-. 2017
- Associations Between β-Amyloid Kinetics and the β-Amyloid Diurnal Pattern in the Central Nervous System.. JAMA neurology. 74:207-215. 2017
- The K-complexes they are a-changin'.. Science translational medicine. 9. 2017
- β-amyloid can't go with the flow.. Science translational medicine. 8:-. 2016
- Comparison of a single-channel EEG sleep study to polysomnography.. Journal of sleep research. 25:625-635. 2016
- An integrated multi-study analysis of intra-subject variability in cerebrospinal fluid amyloid-β concentrations collected by lumbar puncture and indwelling lumbar catheter.. Alzheimer's research & therapy. 7:-. 2015
- How amyloid, sleep and memory connect.. Nature neuroscience. 18:933-4. 2015
- A new model to study sleep deprivation-induced seizure.. Sleep. 38:777-85. 2015
- γ-Hydroxybutyric acid-induced electrographic seizures.. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 10:811-2. 2014
- Amyloid-β diurnal pattern: possible role of sleep in Alzheimer's disease pathogenesis.. Neurobiology of aging. S29-34. 2014
- Dietary and lifestyle guidelines for the prevention of Alzheimer's disease.. Neurobiology of aging. S74-8. 2014
- Continuous 24-hour leptin, proopiomelanocortin, and amino acid measurements in human cerebrospinal fluid: correlations with plasma leptin, soluble leptin receptor, and amino acid levels.. The Journal of clinical endocrinology and metabolism. 99:2540-8. 2014
- Sleep and Alzheimer disease pathology--a bidirectional relationship.. Nature reviews. Neurology. 10:115-9. 2013
- A patient with rhythmic movements during REM sleep. Narcolepsy with cataplexy associated with sleep-related rhythmic movements.. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 9:620-3. 2013
- Teaching Video NeuroImages: phenytoin-induced orofacial dyskinesias.. Neurology. 79:-. 2012
- Relationship of depression and catastrophizing to pain, disability, and medication adherence in patients with HIV-associated sensory neuropathy.. AIDS care. 23:921-8. 2011
- Profound oxygen desaturation due to central apneas associated with interictal generalized spike-wave discharges.. Sleep medicine. 12:302-5. 2011
- Paroxysmal arousals and myoclonic movements associated with interictal epileptiform discharges in NREM and REM sleep.. Clinical neurology and neurosurgery. 113:419-22. 2011
- Seizures and driving restrictions: the unique perspective of military practitioners.. Military medicine. 175:86-7. 2010
- Henrietta Lacks, HeLa cells, and cell culture contamination.. Archives of pathology & laboratory medicine. 133:1463-7. 2009
- The utility of conductive plastic electrodes in prolonged ICU EEG monitoring.. Neurocritical care. 10:368-72. 2008
- Did Sir William Osler perform an autopsy at the Johns Hopkins Hospital?. Archives of pathology & laboratory medicine. 132:261-4. 2008
- Electrical status epilepticus during sleep in an adult.. Sleep medicine. 9:332-4. 2007
- Transient encephalopathy in a postoperative non-alcoholic female with Marchiafava-Bignami disease.. Clinical neurology and neurosurgery. 109:713-5. 2007
- Max brödel: illustrating healed valve ring abscesses.. Archives of pathology & laboratory medicine. 129:1155-8. 2005
- William H. Welch, MD, and the discovery of Bacillus welchii.. Archives of pathology & laboratory medicine. 128:1193-5. 2004
- Vascular gene expression in nonneoplastic and malignant brain.. The American journal of pathology. 165:601-8. 2004
- Spinal meningioma causing diffuse leptomeningeal enhancement.. Neurology. 60:350-1. 2003
- Marked calvarial thickening and dural changes following chronic ventricular shunting for shaken baby syndrome.. Archives of pathology & laboratory medicine. 127:94-7. 2003