authors
- Al La Spada, MD, PhD
- Smith, A C
- Martinez, R A
- Koszdin, K L
- Treuting, P M
- Ware, C B
- Hurley, J B
- Ptácek, L J
- Chen, S
- Fu, Y H
- Sopher, B L
- Libby, R T
- Wang, X
- Li, L Y
- Einum, D D
- Huang, J
- Possin, D E
Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7.
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Overview
publication date
- January 1, 2001
published in
- Neuron Journal
has subject area
- Age Factors
- Animals
- Ataxin-7
- Cell Line
- Cell Nucleus
- Disease Models, Animal
- Electroretinography
- Eye Proteins
- Gene Expression Profiling
- Genes, Synthetic
- Homeodomain Proteins
- Humans
- Macromolecular Substances
- Mice
- Mice, Transgenic
- Nerve Tissue Proteins
- Nuclear Proteins
- Peptides
- Photoreceptor Cells, Vertebrate
- Prions
- Promoter Regions, Genetic
- Protein Binding
- Retinal Degeneration
- Spinocerebellar Ataxias
- Synaptic Transmission
- Trans-Activators
- Transcriptional Activation
- Transfection
- Transgenes
- Trinucleotide Repeats
- Two-Hybrid System Techniques