publication venue for
- Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.. 112:-. 2024
- Harnessing diversity to study Alzheimer's disease: A new iPSC resource from the NIH CARD and ADNI.. 112:694-697. 2024
- Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins.. 112:1100-1109.e5. 2024
- Selective vulnerability of layer 5a corticostriatal neurons in Huntington's disease.. 112:924-941.e10. 2024
- Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.. 112:384-403.e8. 2023
- Hepatic soluble epoxide hydrolase: A promising target for unveiling the liver-brain axis in Alzheimer's disease.. 111:2775-2777. 2023
- PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior.. 111:2709-2726.e9. 2023
- An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.. 111:2383-2398.e7. 2023
- TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.. 111:202-219.e7. 2022
- Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease.. 110:2422-2437.e9. 2022
- ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias.. 110:1304-1317. 2022
- TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease.. 109:3758-3774.e11. 2021
- Aducanumab and the "post-amyloid" era of Alzheimer research?. 109:3045-3047. 2021
- Effects of COVID-19 on preclinical and clinical research in neurology: Examples from research on neurodegeneration and Alzheimer's disease.. 109:3199-3202. 2021
- Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms.. 109:2413-2426.e7. 2021
- C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation.. 109:2275-2291.e8. 2021
- Building brain capital.. 109:1430-1432. 2021
- Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia.. 109:1657-1674.e7. 2021
- Targeting pre-synaptic tau accumulation: a new strategy to counteract tau-mediated synaptic loss and memory deficits.. 109:741-743. 2021
- Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis.. 109:205-221. 2020
- An Open Resource for Non-human Primate Optogenetics.. 108:1075-1090.e6. 2020
- A Novel Neurovascular Liaison Governing the Blood-Brain Barrier.. 107:205-207. 2020
- What Is the Relationship between Pain and Emotion? Bridging Constructs and Communities.. 107:17-21. 2020
- Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.. 107:496-508.e6. 2020
- SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury.. 107:257-273.e5. 2020
- Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways.. 106:727-742.e6. 2020
- Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7.. 105:630-644.e9. 2019
- Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease.. 103:627-641.e7. 2019
- Harnessing Immunoproteostasis to Treat Neurodegenerative Disorders.. 101:1003-1015. 2019
- Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response.. 99:914-924.e3. 2018
- Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.. 96:1013-1023.e4. 2017
- ApoE4 Accelerates Early Seeding of Amyloid Pathology.. 96:1024-1032.e3. 2017
- Building Bridges through Science.. 96:730-735. 2017
- RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2.. 95:1292-1305.e5. 2017
- Elucidating the Role of TREM2 in Alzheimer's Disease.. 94:237-248. 2017
- Synaptic Plasticity onto Dopamine Neurons Shapes Fear Learning.. 93:425-440. 2017
- Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo.. 92:796-812. 2016
- Not Your Father's, or Mother's, Rodent: Moving Beyond B6.. 91:1185-1186. 2016
- Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci.. 87:1215-1233. 2015
- IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior.. 85:519-33. 2015
- Re-evaluation of the Blood-Brain Barrier in the Presence of Alzheimer's Disease Pathology.. 88:237-9. 2015
- The evolution of preclinical Alzheimer's disease: implications for prevention trials.. 84:608-22. 2014
- Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy.. 82:295-307. 2014
- Motor neuron death in ALS: programmed by astrocytes?. 81:961-963. 2014
- Anti-tau antibodies: hitting the target.. 80:254-6. 2013
- Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders.. 77:235-42. 2013
- Using whole-exome sequencing to identify inherited causes of autism.. 77:259-73. 2013
- Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.. 80:402-414. 2013
- Biomarker modeling of Alzheimer's disease.. 80:1347-58. 2013
- GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.. 78:256-68. 2013
- Intercellular (mis)communication in neurodegenerative disease.. 73:886-901. 2012
- Stealth attack: plaque-specific antibody allows for efficient Aβ removal without side effects.. 76:859-61. 2012
- CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA.. 70:1071-84. 2011
- Anti-aβ therapeutics in Alzheimer's disease: the need for a paradigm shift.. 69:203-13. 2011
- Sorting out frontotemporal dementia?. 68:601-3. 2010
- Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics.. 66:835-47. 2010
- Genetic animal models of Parkinson's disease.. 66:646-61. 2010
- Amyloid deposition is associated with impaired default network function in older persons without dementia.. 63:178-88. 2009
- Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.. 64:632-44. 2009
- The role of apolipoprotein E in Alzheimer's disease.. 63:287-303. 2009
- ApoE promotes the proteolytic degradation of Abeta.. 58:681-93. 2008
- Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo.. 58:42-51. 2008
- A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.. 54:739-54. 2007
- Picking up the pieces: the roles of functional remnants of calpain-mediated proteolysis.. 53:317-9. 2007
- A core system for the implementation of task sets.. 50:799-812. 2006
- Parkin blushed by PINK1.. 50:527-9. 2006
- Silencing polyglutamine degeneration with RNAi.. 48:715-8. 2005
- Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.. 47:191-199. 2005
- The power of the dark side: Huntington's disease protein and p53 form a deadly alliance.. 47:1-3. 2005
- Homing in on intracellular Abeta?. 45:639-42. 2005
- Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.. 48:913-22. 2005
- The bad seed in Alzheimer's disease.. 47:167-8. 2005
- Parkin and Hsp70 sacked by BAG5.. 44:899-901. 2004
- Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration.. 41:687-99. 2004
- ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.. 41:193-202. 2004
- Caught in the act: alpha-synuclein is the culprit in Parkinson's disease.. 40:453-6. 2003
- Polyglutamines stop traffic: axonal transport as a common target in neurodegenerative diseases.. 40:1-2. 2003
- Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.. 39:409-21. 2003
- Polyglutamines placed into context.. 38:681-4. 2003
- Animal models of PD: pieces of the same puzzle?. 35:219-22. 2002
- Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7.. 31:913-27. 2001
- Imaging physiologic dysfunction of individual hippocampal subregions in humans and genetically modified mice.. 28:653-64. 2000
- Synaptic innervation density is regulated by neuron-derived BDNF.. 18:257-67. 1997
- Widespread expression of Huntington's disease gene (IT15) protein product.. 14:1065-74. 1995
- Nitric oxide mediates the formation of synaptic connections in developing and regenerating olfactory receptor neurons.. 13:289-99. 1994
- Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids.. 11:371-86. 1993
- Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase.. 7:615-24. 1991
- Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR.. 4:253-67. 1990