authors
- Kim, Jungsu
- Castellano, Joseph M
- Jiang, Hong
- Basak, Jacob M
- Parsadanian, Maia
- Pham, Vi
- Mason, Stephanie M
- Paul, Steven M
- David M. Holtzman, MD
Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.
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Overview
publication date
- January 1, 2009
published in
- Neuron Journal
has subject area
- Amyloid
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Animals
- Animals, Newborn
- Apolipoproteins E
- Astrocytes
- Brain
- CD11b Antigen
- Cells, Cultured
- Embryo, Mammalian
- Extracellular Space
- Female
- Gene Expression Regulation
- Humans
- Leukocyte Common Antigens
- Mice
- Mice, Transgenic
- Neurons
- Presenilin-1
- Receptors, LDL