IL-12p40(-/-) mice treated with intratracheal bleomycin exhibit decreased pulmonary inflammation and increased fibrosis.
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Overview
publication date
- January 2002
published in
has subject area
- Animals
- Anti-Bacterial Agents
- Bleomycin
- Bronchoalveolar Lavage Fluid
- Chemokine CCL11
- Chemokine CCL5
- Chemokines, CC
- Female
- Hydroxyproline
- Interferon-gamma
- Interleukin-10
- Interleukin-12
- Interleukin-6
- Killer Cells, Natural
- Leukocytes, Mononuclear
- Lung
- Macrophages, Alveolar
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Monocytes
- Pneumonia
- Pulmonary Fibrosis
- Spleen