authors
- Cirrito, John R
- Paul, Steven M
- DeMattos, Ronald B
- David M. Holtzman, MD
- May, Patrick C
- O'Dell, Mark A
- Taylor, Jennie W
- Parsadanian, Maia
- Cramer, Jeffrey W
- Audia, James E
- Nissen, Jeffrey S
- Bales, Kelly R
In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life.
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Overview
publication date
- January 1, 2003
published in
has subject area
- Age Factors
- Alzheimer Disease
- Amyloid Precursor Protein Secretases
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Animals
- Aspartic Acid Endopeptidases
- Brain
- Cerebral Cortex
- Cerebrospinal Fluid
- Disease Progression
- Endopeptidases
- Enzyme Inhibitors
- Enzyme-Linked Immunosorbent Assay
- Extracellular Space
- Hippocampus
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Microdialysis
- Plaque, Amyloid