authors
- Fryer, John D
- Simmons, Kelly
- Parsadanian, Maia
- Bales, Kelly R
- Paul, Steven M
- Sullivan, Patrick M
- David M. Holtzman, MD
Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.
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Overview
publication date
- January 1, 2005
published in
has subject area
- Alkenes
- Alzheimer Disease
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Animals
- Apolipoprotein E3
- Apolipoprotein E4
- Apolipoproteins E
- Benzoates
- Blood Vessels
- Cerebral Amyloid Angiopathy
- Disease Models, Animal
- Enzyme-Linked Immunosorbent Assay
- Gene Expression Regulation
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Peptide Fragments
- Plaque, Amyloid