authors
- Mazzulli, Joseph R
- Mishizen, Amanda J
- Giasson, Benoit I
- David Lynch, MD, PhD
- Thomas, Steven A
- Nakashima, Akira
- Nagatsu, Toshiharu
- Ota, Akira
- Ischiropoulos, Harry
Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates.
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Overview
publication date
- January 1, 2006
published in
has subject area
- 3,4-Dihydroxyphenylacetic Acid
- Amino Acid Substitution
- Animals
- Catechols
- Cell Differentiation
- Cell Line, Tumor
- Cerebral Cortex
- Corpus Striatum
- Cytosol
- Dopamine
- Humans
- Levodopa
- Mice
- Mice, Transgenic
- Mutation, Missense
- Nerve Degeneration
- Neuroblastoma
- Oxidation-Reduction
- Parkinson Disease
- Parkinsonian Disorders
- Protein Conformation
- Recombinant Fusion Proteins
- Solubility
- Transfection
- Tretinoin
- Tyrosine 3-Monooxygenase
- alpha-Synuclein