authors
- Mookerjee, Shona
- Al La Spada, MD, PhD
- Ellerby, Lisa M
- Papanikolaou, Theodora
- Guyenet, Stephan J
- Sampath, Vanitha
- Lin, Amy
- Vitelli, Cathy
- DeGiacomo, Francesco
- Sopher, Bryce L
- Chen, Sylvia F
Posttranslational modification of ataxin-7 at lysine 257 prevents autophagy-mediated turnover of an N-terminal caspase-7 cleavage fragment.
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Overview
publication date
- January 1, 2009
published in
has subject area
- Acetylation
- Animals
- Animals, Newborn
- Ataxin-7
- Autophagy
- Caspase 7
- Cells, Cultured
- Cerebellum
- Disease Models, Animal
- Histone Deacetylases
- Humans
- Lysosomal-Associated Membrane Protein 2
- Mice
- Mice, Transgenic
- Mucoproteins
- Nerve Tissue Proteins
- Neurons
- Peptides
- Prions
- Protein Processing, Post-Translational
- Protein Subunits
- RNA Interference
- Spinocerebellar Ataxias
- Transfection