Activation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein.
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Overview
publication date
- January 1, 2011
published in
has subject area
- Animals
- Calcium
- Calcium-Calmodulin-Dependent Protein Kinase Type 2
- Cell Nucleus
- Cytoplasm
- Cytoskeletal Proteins
- Genes, Immediate-Early
- Glutamic Acid
- Intracellular Space
- Mice
- Mitogen-Activated Protein Kinase 1
- Mitogen-Activated Protein Kinase 3
- Neostriatum
- Nerve Tissue Proteins
- Neurons
- Rats
- Receptor, Metabotropic Glutamate 5
- Receptors, Metabotropic Glutamate
- Serum Response Factor
- Synaptic Transmission
- Up-Regulation