authors
- Turnbaugh, Jessie A
- Harris, David A
- Unterberger, Ursula
- Saá, Paula
- Massignan, Tania
- Fluharty, Brian R
- Bowman, Frederick P
- Michael Miller, MD, PhD
- Supattapone, Surachai
- Biasini, Emiliano
The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc).
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Overview
publication date
- January 1, 2012
published in
has subject area
- Age Factors
- Animals
- Brain
- Cell Line, Transformed
- Cricetinae
- Disease Models, Animal
- Endocytosis
- Gene Expression Regulation
- Humans
- Immunization
- Membrane Microdomains
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Neuroblastoma
- Peptide Fragments
- PrPC Proteins
- PrPSc Proteins
- Prion Diseases
- Protein Binding
- Protein Structure, Secondary
- Scrapie
- Sequence Deletion
- Time Factors
- Transfection