authors
- Chen, Yaomin
- Huang, Xiumei
- Zhang, Yun-wu
- Rockenstein, Edward
- Bu, Guojun
- Todd Golde, MD, PhD
- Masliah, Eliezer
- Xu, Huaxi
Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.
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Overview
publication date
- January 1, 2012
published in
has subject area
- Amyloid Precursor Protein Secretases
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Animals
- Aspartic Acid Endopeptidases
- Brain
- CREB-Binding Protein
- Cells, Cultured
- Colforsin
- Cyclic AMP
- Cyclic AMP-Dependent Protein Kinases
- Disks Large Homolog 4 Protein
- Embryo, Mammalian
- Gene Expression Regulation
- Green Fluorescent Proteins
- Guanylate Kinases
- MARVEL Domain-Containing Proteins
- Membrane Proteins
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation
- Neuroblastoma
- Phosphorylation
- Proteolipids
- Signal Transduction
- Synaptophysin
- Transfection