authors
- Harbut, Michael B
- Diagana, Thierry T
- Greenbaum, Doron C
- Patel, Bhumit A
- Yeung, Bryan K S
- McNamara, Case W
- Bright, A Taylor
- Ballard, Jaime
- Supek, Frantisek
- Todd Golde, MD, PhD
- Winzeler, Elizabeth A
Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design.
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Overview
publication date
- January 1, 2012
published in
has subject area
- Animals
- Antiparasitic Agents
- Aspartic Acid Endopeptidases
- Base Sequence
- Computational Biology
- Drug Design
- Drug Resistance
- Endoplasmic Reticulum Stress
- Endoplasmic Reticulum-Associated Degradation
- Hep G2 Cells
- Humans
- Life Cycle Stages
- Liver
- Molecular Sequence Data
- Parasites
- Plasmodium falciparum
- Protease Inhibitors
- Proteasome Inhibitors
- Proteolysis
- Proteome
- Small Molecule Libraries
- Toxoplasma
- Trypanosoma cruzi