authors
- Weil, Amy F
- Ghosh, Devlina
- Zhou, Yan
- Seiple, Lauren
- McMahon, Moira A
- Adam Spivak, MD, FACP
- Siliciano, Robert F
- Stivers, James T
Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration.
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Overview
publication date
- January 1, 2013
published in
has subject area
- Anti-HIV Agents
- Base Sequence
- CD4-Positive T-Lymphocytes
- DNA Glycosylases
- DNA, Viral
- Deoxyuracil Nucleotides
- Enzyme Inhibitors
- Gene Knockdown Techniques
- HIV-1
- HT29 Cells
- Host-Pathogen Interactions
- Humans
- Immunity, Innate
- Macrophages
- Models, Biological
- Mutation
- Quinazolines
- Reverse Transcription
- Thiophenes
- Thymidine
- Thymidylate Synthase
- Virion
- Virus Integration