authors
- Hurez, Vincent
- Padrón, Álvaro
- Drerup, Justin
- Liu, Yang
- Hasty, Paul
- Sharp, Zelton Dave
- Curiel, Tyler J
- Dao, Vinh
- Liu, Aijie
- Pandeswara, Srilakshmi
- Gelfond, Jonathan
- Sun, Lishi
- Bergman, Molly
- Orihuela, Carlos J
- Galvan, Veronica
Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice.
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Overview
publication date
- August 28, 2015
published in
- Aging cell Journal
has subject area
- Aging
- Animals
- Antibiotics, Antineoplastic
- B-Lymphocytes
- CD8-Positive T-Lymphocytes
- Cell Differentiation
- Dendritic Cells
- Female
- Flagellin
- Gastrointestinal Microbiome
- Gene Expression Profiling
- Immunologic Memory
- Interleukin-22
- Interleukins
- Longevity
- Male
- Melanoma, Experimental
- Mice
- Mice, Inbred C57BL
- Myeloid Cells
- Programmed Cell Death 1 Receptor
- Sirolimus
- Spleen
- T-Lymphocytes, Regulatory
- TOR Serine-Threonine Kinases