Aging cell
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Overview
publication venue for
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An interpretable machine learning-based cerebrospinal fluid proteomics clock for predicting age reveals novel insights into brain aging..
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2024
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Aging-associated decrease of PGC-1α promotes pain chronification..
23:-.
2024
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Effect of long-term caloric restriction on telomere length in healthy adults: CALERIE™ 2 trial analysis..
23:-.
2024
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Implications of metabolism on multi-systems healthy aging across the lifespan..
23:-.
2024
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Effect of canakinumab on frailty: A post hoc analysis of the CANTOS trial..
23:-.
2023
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Skeletal muscle DNA methylation: Effects of exercise and HIV..
23:-.
2023
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Associations between skeletal muscle energetics and accelerometry-based performance fatigability: Study of Muscle, Mobility and Aging..
23:-.
2023
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Proteomic architecture of frailty across the spectrum of cardiovascular disease..
22:-.
2023
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Holistic frailty prevention: The promise of movement-based mind-body therapies..
23:-.
2023
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Longitudinal analysis of physical function in older adults: The effects of physical inactivity and exercise training..
23:-.
2023
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Sex- and APOE-specific genetic risk factors for late-onset Alzheimer's disease: Evidence from gene-gene interaction of longevity-related loci..
22:-.
2023
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Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice..
22:-.
2023
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Nanopore sequencing identifies a higher frequency and expanded spectrum of mitochondrial DNA deletion mutations in human aging..
22:-.
2023
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Mitochondrial function declines with age within individuals but is not linked to the pattern of growth or mortality risk in zebra finch..
22:-.
2023
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Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging..
22:-.
2023
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Age-associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis..
22:-.
2023
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SIRT3 deficiency decreases oxidative metabolism capacity but increases lifespan in male mice under caloric restriction..
21:-.
2022
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Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice..
21:-.
2022
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Cap-independent translation of GPLD1 enhances markers of brain health in long-lived mutant and drug-treated mice..
21:-.
2022
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Integrity of hypothalamic-pituitary-testicular axis in exceptional longevity..
21:-.
2022
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Nicotinamide riboside and caffeine partially restore diminished NAD availability but not altered energy metabolism in Alzheimer's disease..
21:-.
2022
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Neuroprotective effects of Canagliflozin: Lessons from aged genetically diverse UM-HET3 mice..
21:-.
2022
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Protein restriction and branched-chain amino acid restriction promote geroprotective shifts in metabolism..
21:-.
2022
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Transcriptional landscape of human microglia implicates age, sex, and APOE-related immunometabolic pathway perturbations..
21:-.
2022
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Geroscience-guided repurposing of FDA-approved drugs to target aging: A proposed process and prioritization..
21:-.
2022
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Geroscience-guided repurposing of FDA-approved drugs to target aging: A proposed process and prioritization..
21:e13596.
2022
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The antagonistic pleiotropy of insulin-like growth factor 1..
20:-.
2021
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Senolytics alleviate the degenerative disorders of temporomandibular joint in old age..
20:-.
2021
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Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury..
20:-.
2021
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Circulating microRNA profile in humans and mice with congenital GH deficiency..
20:-.
2021
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Increasing skeletal muscle carnitine content in older individuals increases whole-body fat oxidation during moderate-intensity exercise..
20:-.
2021
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Plasma proteomic profile of age, health span, and all-cause mortality in older adults..
19:-.
2020
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Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling..
19:-.
2020
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Similar burden of pathogenic coding variants in exceptionally long-lived individuals and individuals without exceptional longevity..
19:-.
2020
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Plasma proteomic profile of frailty..
19:-.
2020
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Exercise training reverses cardiac aging phenotypes associated with heart failure with preserved ejection fraction in male mice..
19:-.
2020
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A lncRNA survey finds increases in neuroprotective LINC-PINT in Parkinson's disease substantia nigra..
19:-.
2020
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Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice..
19:-.
2020
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Transplanting cells from old but not young donors causes physical dysfunction in older recipients..
19:-.
2020
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Mobilization-based transplantation of young-donor hematopoietic stem cells extends lifespan in mice..
19:-.
2020
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Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants..
18:-.
2019
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Hypothalamic mTORC2 is essential for metabolic health and longevity..
18:-.
2019
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Glycine supplementation extends lifespan of male and female mice..
18:-.
2019
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Targeting senescent cells alleviates obesity-induced metabolic dysfunction..
18:-.
2019
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Genetically heterogeneous mice exhibit a female survival advantage that is age- and site-specific: Results from a large multi-site study..
18:-.
2019
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Conservation of physiological dysregulation signatures of aging across primates..
18:-.
2019
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Acarbose improves health and lifespan in aging HET3 mice..
18:-.
2019
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Microtubule regulators act in the nervous system to modulate fat metabolism and longevity through DAF-16 in C. elegans..
18:-.
2019
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Influenza virus inoculum volume is critical to elucidate age-dependent mortality in mice..
18:-.
2019
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Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson's diseases..
18:-.
2019
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Neuronal-specific proteasome augmentation via Prosβ5 overexpression extends lifespan and reduces age-related cognitive decline..
18:-.
2019
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mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging..
19:-.
2019
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mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism..
18:-.
2019
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Tau protein aggregation is associated with cellular senescence in the brain..
17:-.
2018
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Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype..
17:-.
2018
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The ω-3 fatty acid α-linolenic acid extends Caenorhabditis elegans lifespan via NHR-49/PPARα and oxidation to oxylipins..
16:1125-1135.
2017
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The replicative lifespan-extending deletion of SGF73 results in altered ribosomal gene expression in yeast..
16:785-796.
2017
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Impact of early personal-history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan..
16:644-651.
2017
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Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion..
16:518-528.
2017
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Pathophysiology of heart failure and frailty: a common inflammatory origin?.
16:444-450.
2017
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Biomarker signatures of aging..
16:329-338.
2017
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Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice..
15:973-7.
2016
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Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans..
15:903-13.
2016
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GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium..
15:792-800.
2016
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Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits..
15:811-24.
2016
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Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer..
15:872-84.
2016
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Age-associated vascular inflammation promotes monocytosis during atherogenesis..
15:766-77.
2016
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Mitochondrial metabolites extend lifespan..
15:336-48.
2016
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Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice..
15:155-66.
2015
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Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system..
15:28-38.
2015
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Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: a randomized clinical trial..
15:22-7.
2015
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Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice..
14:945-56.
2015
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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs..
14:644-58.
2015
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Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake..
14:511-23.
2015
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Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan..
13:911-7.
2014
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Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity..
13:769-71.
2014
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Aging is associated with increased regulatory T-cell function..
13:441-8.
2014
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Inhibition of x-box binding protein 1 reduces tunicamycin-induced apoptosis in aged murine macrophages..
12:794-801.
2013
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Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive..
12:712-8.
2013
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Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile..
12:645-51.
2013
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The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection..
11:912-5.
2012
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Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly..
11:104-10.
2011
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Stem cell review series: aging of the skeletal muscle stem cell niche..
7:590-8.
2008
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Murine [corrected] myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging..
5:473-86.
2006
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DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid..
5:283-91.
2006
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The nuclear hormone receptor DAF-12 has opposing effects on Caenorhabditis elegans lifespan and regulates genes repressed in multiple long-lived worms..
5:127-38.
2006
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Lipophilic regulator of a developmental switch in Caenorhabditis elegans..
3:413-21.
2004
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Pre-mRNA splicing modulations in senescence..
1:10-6.
2002
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mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism
2019
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Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion
2017
Identity
International Standard Serial Number (ISSN)