authors
- Li, Tieshi
- Spagnoli, Anna
- Chubinskaya, Susan
- Esposito, Alessandra
- Jin, Xin
- Tagliafierro, Lidia
- Richard Loeser, MD
- Hakimiyan, Arnavaz A
- Longobardi, Lara
- Ozkan, Huseyin
TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
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Overview
publication date
- January 1, 2019
published in
- Science translational medicine Journal
has subject area
- Aging
- Animals
- Chondrocytes
- Disease Progression
- Down-Regulation
- Humans
- Injections, Intra-Articular
- Interleukin-1
- Joints
- Matrix Metalloproteinase 13
- Mice
- Mice, Knockout
- Molecular Targeted Therapy
- Osteoarthritis
- Phenotype
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Interleukin-1
- Signal Transduction
- Up-Regulation