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2. Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk..  bioRxiv : the preprint server for biology.  2024
3. DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair..  Arthritis & rheumatology (Hoboken, N.J.).  76:842-844. 2024
4. Use of a novel magnetically actuated compression system to study the temporal dynamics of axial and lateral strain in human osteochondral plugs..  Journal of biomechanics.  -. 2023
5. Aging and the emerging role of cellular senescence in osteoarthritis..  Osteoarthritis and cartilage.  32:365-371. 2023
6. Redox-active endosomes mediate α5β1 integrin signaling and promote chondrocyte matrix metalloproteinase production in osteoarthritis..  Science signaling.  16:-. 2023
7. Sirt6.  Annals of the rheumatic diseases.  82:1464-1473. 2023
8. Age and oxidative stress regulate Nrf2 homeostasis in human articular chondrocytes..  Osteoarthritis and cartilage.  31:1214-1223. 2023
9. Yes-associated protein nuclear translocation promotes anabolic activity in human articular chondrocytes..  Osteoarthritis and cartilage.  31:1078-1090. 2023
10. Association of Traumatic Knee Injury With Radiographic Evidence of Knee Osteoarthritis in Military Officers..  Arthritis care & research.  75:1744-1751. 2023
11. Association of plasma microbial composition with a leaky gut in obesity-related osteoarthritis: An exploratory study..  Osteoarthritis and cartilage open.  4:-. 2022
12. Correspondence on 'Mechanical overloading promotes chondrocyte senescence and osteoarthritis development through downregulating FBXW7'..  Annals of the rheumatic diseases.  82:-. 2022
13. Biclustering reveals potential knee OA phenotypes in exploratory analyses: Data from the Osteoarthritis Initiative..  PloS one.  17:-. 2022
14. Targeting cellular senescence as a novel treatment for osteoarthritis..  Current opinion in pharmacology.  -. 2022
15. Association of Increased Serum Lipopolysaccharide, But Not Microbial Dysbiosis, With Obesity-Related Osteoarthritis..  Arthritis & rheumatology (Hoboken, N.J.).  74:227-236. 2022
16. Fecal metabolomics reveals products of dysregulated proteolysis and altered microbial metabolism in obesity-related osteoarthritis..  Osteoarthritis and cartilage.  30:81-91. 2021
17. Tibiofemoral articular cartilage composition differs based on serum biochemical profiles following anterior cruciate ligament reconstruction..  Osteoarthritis and cartilage.  29:1732-1740. 2021
18. Precision Medicine Approach to Develop and Internally Validate Optimal Exercise and Weight-Loss Treatments for Overweight and Obese Adults With Knee Osteoarthritis: Data From a Single-Center Randomized Trial..  Arthritis care & research.  73:693-701. 2021
19. Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee Osteoarthritis: The START Randomized Clinical Trial..  JAMA.  325:646-657. 2021
20. Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes..  Free radical biology & medicine.  90-103. 2021
21. Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review..  JAMA.  325:568-578. 2021
22. Optimization of histologic grading schemes in spontaneous and surgically-induced murine models of osteoarthritis..  Osteoarthritis and cartilage.  29:536-546. 2021
23. Transcriptional response of human articular chondrocytes treated with fibronectin fragments: an in vitro model of the osteoarthritis phenotype..  Osteoarthritis and cartilage.  29:235-247. 2020
24. The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence..  Osteoarthritis and cartilage.  29:402-412. 2020
25. Mechanisms and therapeutic implications of cellular senescence in osteoarthritis..  Nature reviews. Rheumatology.  17:47-57. 2020
26. Reply..  Arthritis & rheumatology (Hoboken, N.J.).  72:2162-2163. 2020
27. Deletion of JNK Enhances Senescence in Joint Tissues and Increases the Severity of Age-Related Osteoarthritis in Mice..  Arthritis & rheumatology (Hoboken, N.J.).  72:1679-1688. 2020
28. Vitamin K Status and Mobility Limitation and Disability in Older Adults: The Health, Aging, and Body Composition Study..  The journals of gerontology. Series A, Biological sciences and medical sciences.  75:792-797. 2020
29. Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation..  JCI insight.  5. 2020
30. The effects of intensive dietary weight loss and exercise on gait in overweight and obese adults with knee osteoarthritis. The Intensive Diet and Exercise for Arthritis (IDEA) trial..  Journal of biomechanics.  -. 2019
31. Phenotypes of osteoarthritis: current state and future implications..  Clinical and experimental rheumatology.  37 Suppl 120:64-72. 2019
32. Naturally occurring osteoarthritis in male mice with an extended lifespan..  Connective tissue research.  61:95-103. 2019
33. TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis..  Science translational medicine.  11. 2019
34. Effect of intensive diet and exercise on self-efficacy in overweight and obese adults with knee osteoarthritis: The IDEA randomized clinical trial..  Translational behavioral medicine.  9:227-235. 2019
35. Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017..  The Journal of rheumatology.  46:976-980. 2019
36. Impaired Annulus Fibrosus Development and Vertebral Fusion Cause Severe Scoliosis in Mice with Deficiency of c-Jun NH2-Terminal Kinases 1 and 2..  The American journal of pathology.  189:868-885. 2019
37. The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis..  The Journal of rheumatology.  46:981-989. 2019
38. Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes..  Free radical biology & medicine.  139-152. 2019
39. Articular chondrocytes isolated from the knee and ankle joints of human tissue donors demonstrate similar redox-regulated MAP kinase and Akt signaling..  Osteoarthritis and cartilage.  27:703-711. 2018
40. Does Joint Injury Make Young Joints Old?.  The Journal of the American Academy of Orthopaedic Surgeons.  26:e455-e456. 2018
41. Intentional Weight Loss in Overweight and Obese Patients With Knee Osteoarthritis: Is More Better?.  Arthritis care & research.  70:1569-1575. 2018
42. Reactive oxygen species, aging and articular cartilage homeostasis..  Free radical biology & medicine.  73-82. 2018
43. Osteoarthritis induced by destabilization of the medial meniscus is reduced in germ-free mice..  Osteoarthritis and cartilage.  26:1098-1109. 2018
44. Association of Vitamin K Status Combined With Vitamin D Status and Lower-Extremity Function: A Prospective Analysis of Two Knee Osteoarthritis Cohorts..  Arthritis care & research.  70:1150-1159. 2018
45. Alterations in quadriceps muscle cellular and molecular properties in adults with moderate knee osteoarthritis..  Osteoarthritis and cartilage.  26:1359-1368. 2018
46. Is osteoarthritis one disease or a collection of many?.  Rheumatology (Oxford, England).  57:iv34-iv42. 2018
47. Time between anterior cruciate ligament injury and reconstruction and cartilage metabolism six-months following reconstruction..  The Knee.  25:296-305. 2018
48. Targeting aging for disease modification in osteoarthritis..  Current opinion in rheumatology.  30:101-107. 2018
49. Effects of dietary weight loss with and without exercise on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the Intensive Diet and Exercise for Arthritis trial (IDEA)..  Osteoarthritis and cartilage.  25:1822-1828. 2017
50. Wnt5a induces catabolic signaling and matrix metalloproteinase production in human articular chondrocytes..  Osteoarthritis and cartilage.  25:1505-1515. 2017
51. High fat-diet and saturated fatty acid palmitate inhibits IGF-1 function in chondrocytes..  Osteoarthritis and cartilage.  25:1516-1521. 2017
52. Biochemical markers of cartilage metabolism are associated with walking biomechanics 6-months following anterior cruciate ligament reconstruction..  Journal of orthopaedic research : official publication of the Orthopaedic Research Society.  35:2288-2297. 2017
53. A mouse model for chronic pain-induced increase in ethanol consumption..  Pain.  158:457-462. 2017
54. Impact of Diet and/or Exercise Intervention on Infrapatellar Fat Pad Morphology: Secondary Analysis from the Intensive Diet and Exercise for Arthritis (IDEA) Trial..  Cells, tissues, organs.  203:258-266. 2017
55. Weight-loss and exercise for communities with arthritis in North Carolina (we-can): design and rationale of a pragmatic, assessor-blinded, randomized controlled trial..  BMC musculoskeletal disorders.  18:-. 2017
56. Reduced Osteoarthritis Severity in Aged Mice With Deletion of Macrophage Migration Inhibitory Factor..  Arthritis & rheumatology (Hoboken, N.J.).  69:352-361. 2017
57. The Role of Aging in the Development of Osteoarthritis..  Transactions of the American Clinical and Climatological Association.  44-54. 2017
58. Role of the C-C chemokine receptor-2 in a murine model of injury-induced osteoarthritis..  Osteoarthritis and cartilage.  25:914-925. 2016
59. Relationship of Objectively-Measured Habitual Physical Activity to Chronic Inflammation and Fatigue in Middle-Aged and Older Adults..  The journals of gerontology. Series A, Biological sciences and medical sciences.  71:1437-1443. 2016
60. Ageing and the pathogenesis of osteoarthritis..  Nature reviews. Rheumatology.  12:412-20. 2016
61. Association of urinary metabolites with radiographic progression of knee osteoarthritis in overweight and obese adults: an exploratory study..  Osteoarthritis and cartilage.  24:1479-86. 2016
62. Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes..  The Journal of biological chemistry.  291:6641-54. 2016
63. Reduced response of human meniscal cells to Osteogenic Protein 1 during osteoarthritis and pro-inflammatory stimulation..  Osteoarthritis and cartilage.  24:1036-46. 2016
64. Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments..  Arthritis & rheumatology (Hoboken, N.J.).  68:117-26. 2016
65. Vitamin K Status and Lower Extremity Function in Older Adults: The Health Aging and Body Composition Study..  The journals of gerontology. Series A, Biological sciences and medical sciences.  71:1348-55. 2015
66. Aging-related inflammation in osteoarthritis..  Osteoarthritis and cartilage.  23:1966-71. 2015
67. Editorial: inflammatory activity in symptomatic knee osteoarthritis: not all inflammation is local..  Arthritis & rheumatology (Hoboken, N.J.).  67:2797-800. 2015
68. Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion..  Osteoarthritis and cartilage.  23:1780-9. 2015
69. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increased in osteoarthritis and regulates chondrocyte catabolic and anabolic activities..  Osteoarthritis and cartilage.  23:1523-31. 2015
70. The Intensive Diet and Exercise for Arthritis (IDEA) trial: 18-month radiographic and MRI outcomes..  Osteoarthritis and cartilage.  23:1090-8. 2015
71. Function of the chondrocyte PI-3 kinase-Akt signaling pathway is stimulus dependent..  Osteoarthritis and cartilage.  23:949-56. 2015
72. The association between vitamin K status and knee osteoarthritis features in older adults: the Health, Aging and Body Composition Study..  Osteoarthritis and cartilage.  23:370-8. 2014
73. Effects of total and regional fat loss on plasma CRP and IL-6 in overweight and obese, older adults with knee osteoarthritis..  Osteoarthritis and cartilage.  23:249-56. 2014
74. Redox regulation of Rac1 by thiol oxidation..  Free radical biology & medicine.  237-50. 2014
75. Knee joint loading in knee osteoarthritis: influence of abdominal and thigh fat..  Medicine and science in sports and exercise.  46:1677-83. 2014
76. Integrins and chondrocyte-matrix interactions in articular cartilage..  Matrix biology : journal of the International Society for Matrix Biology.  11-6. 2014
77. Aging and oxidative stress reduce the response of human articular chondrocytes to insulin-like growth factor 1 and osteogenic protein 1..  Arthritis & rheumatology (Hoboken, N.J.).  66:2201-9. 2014
78. Influences of alignment and obesity on knee joint loading in osteoarthritic gait..  Osteoarthritis and cartilage.  22:912-7. 2014
79. Brief report: stress-inducible nuclear protein 1 regulates matrix metalloproteinase 13 expression in human articular chondrocytes..  Arthritis & rheumatology (Hoboken, N.J.).  66:1266-71. 2014
80. The independent and combined effects of intensive weight loss and exercise training on bone mineral density in overweight and obese older adults with osteoarthritis..  Osteoarthritis and cartilage.  22:726-33. 2014
81. Integration of gene expression data with network-based analysis to identify signaling and metabolic pathways regulated during the development of osteoarthritis..  Gene.  542:38-45. 2014
82. Pro-inflammatory stimulation of meniscus cells increases production of matrix metalloproteinases and additional catabolic factors involved in osteoarthritis pathogenesis..  Osteoarthritis and cartilage.  22:264-74. 2013
83. Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial..  JAMA.  310:1263-73. 2013
84. Strength Training for Arthritis Trial (START): design and rationale..  BMC musculoskeletal disorders.  -. 2013
85. Osteoarthritis year in review 2013: biology..  Osteoarthritis and cartilage.  21:1436-42. 2013
86. Rac1 is required for matrix metalloproteinase 13 production by chondrocytes in response to fibronectin fragments..  Arthritis and rheumatism.  65:1561-8. 2013
87. Disease progression and phasic changes in gene expression in a mouse model of osteoarthritis..  PloS one.  8:-. 2013
88. Aging processes and the development of osteoarthritis..  Current opinion in rheumatology.  25:108-13. 2013
89. Ionizing radiation causes active degradation and reduces matrix synthesis in articular cartilage..  International journal of radiation biology.  89:268-77. 2012
90. Histopathology of naturally occurring and surgically induced osteoarthritis in mice..  Osteoarthritis and cartilage.  20:949-56. 2012
91. Effects of aging on articular cartilage homeostasis..  Bone.  51:241-8. 2012
92. Osteoarthritis: a disease of the joint as an organ..  Arthritis and rheumatism.  64:1697-707. 2012
93. Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice..  Arthritis and rheumatism.  64:705-17. 2012
94. Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes..  Arthritis research & therapy.  14:-. 2012
95. The effects of aging on the development of osteoarthritis..  HSS journal : the musculoskeletal journal of Hospital for Special Surgery.  8:18-9. 2011
96. A Comprehensive Histological Assessment of Osteoarthritis Lesions in Mice..  Cartilage.  2:354-63. 2011
97. Aging and osteoarthritis..  Current opinion in rheumatology.  23:492-6. 2011
98. A comprehensive 3-year internal medicine residency research curriculum..  The American journal of medicine.  124:469-73. 2011
99. Regulation of chondrocyte gene expression by osteogenic protein-1..  Arthritis research & therapy.  13:-. 2011
100. Does high weight loss in older adults with knee osteoarthritis affect bone-on-bone joint loads and muscle forces during walking?.  Osteoarthritis and cartilage.  19:272-80. 2010
101. Sumoylation and nuclear translocation of S100A4 regulate IL-1beta-mediated production of matrix metalloproteinase-13..  The Journal of biological chemistry.  285:31517-24. 2010
102. Age-related changes in the musculoskeletal system and the development of osteoarthritis..  Clinics in geriatric medicine.  26:371-86. 2010
103. p38gamma mitogen-activated protein kinase suppresses chondrocyte production of MMP-13 in response to catabolic stimulation..  Osteoarthritis and cartilage.  18:1203-10. 2010
104. Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes..  Journal of cellular biochemistry.  110:573-80. 2010
105. Biosynthesis of the vitamin K-dependent matrix Gla protein (MGP) in chondrocytes: a fetuin-MGP protein complex is assembled in vesicles shed from normal but not from osteoarthritic chondrocytes..  Osteoarthritis and cartilage.  18:1096-103. 2010
106. Why is osteoarthritis an age-related disease?.  Best practice & research. Clinical rheumatology.  24:15-26. 2010
107. Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways..  The Journal of biological chemistry.  284:31972-81. 2009
108. The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale..  BMC musculoskeletal disorders.  -. 2009
109. Articular cartilage nuclear receptors: an emerging target for treatment of osteoarthritis..  Osteoarthritis and cartilage.  17:829-31. 2009
110. Cost-effectiveness of exercise and diet in overweight and obese adults with knee osteoarthritis..  Medicine and science in sports and exercise.  41:1167-74. 2009
111. Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix..  Osteoarthritis and cartilage.  17:971-9. 2009
112. Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes..  Arthritis and rheumatism.  60:792-800. 2009
113. Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis..  Arthritis and rheumatism.  60:492-500. 2009
114. Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage..  Osteoarthritis and cartilage.  17:513-7. 2008
115. Mitogen-activated protein kinases as therapeutic targets in osteoarthritis..  Current opinion in rheumatology.  20:581-6. 2008
116. Effect of an exercise and dietary intervention on serum biomarkers in overweight and obese adults with osteoarthritis of the knee..  Osteoarthritis and cartilage.  16:1047-53. 2008
117. Inflammatory biomarkers and physical function in older, obese adults with knee pain and self-reported osteoarthritis after intensive weight-loss therapy..  Journal of the American Geriatrics Society.  56:644-51. 2008
118. Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13..  Arthritis research & therapy.  10:-. 2008
119. Cell death in osteoarthritis..  Current rheumatology reports.  10:37-42. 2008
120. Molecular mechanisms of cartilage destruction in osteoarthritis..  Journal of musculoskeletal & neuronal interactions.  8:303-6. 2008
121. Translational research in osteoarthritis--from molecules to animals to humans..  Journal of musculoskeletal & neuronal interactions.  8:301-2. 2008
122. Glucosamine/chondroitin combined with exercise for the treatment of knee osteoarthritis: a preliminary study..  Osteoarthritis and cartilage.  15:1256-66. 2007
123. Functional integrin subunits regulating cell-matrix interactions in the intervertebral disc..  Journal of orthopaedic research : official publication of the Orthopaedic Research Society.  25:829-40. 2007
124. Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes..  The Journal of biological chemistry.  282:11110-21. 2007
125. Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments..  Free radical biology & medicine.  42:1350-8. 2007
126. Effects of chronic growth hormone and insulin-like growth factor 1 deficiency on osteoarthritis severity in rat knee joints..  Arthritis and rheumatism.  54:3850-8. 2006
127. Synergistic effect of IGF-1 and OP-1 on matrix formation by normal and OA chondrocytes cultured in alginate beads..  Osteoarthritis and cartilage.  15:421-30. 2006
128. Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products..  Arthritis and rheumatism.  54:2901-11. 2006
129. Intensive weight loss program improves physical function in older obese adults with knee osteoarthritis..  Obesity (Silver Spring, Md.).  14:1219-30. 2006
130. Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide..  Arthritis and rheumatism.  54:1357-60. 2006
131. Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytes..  Arthritis and rheumatism.  52:3910-7. 2005
132. Chondrocyte cell death mediated by reactive oxygen species-dependent activation of PKC-betaI..  American journal of physiology. Cell physiology.  290:C802-11. 2005
133. Increased matrix metalloproteinase-13 production with aging by human articular chondrocytes in response to catabolic stimuli..  The journals of gerontology. Series A, Biological sciences and medical sciences.  60:1118-24. 2005
134. Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis..  Arthritis and rheumatism.  52:2376-85. 2005
135. IGF-I stimulation of proteoglycan synthesis by chondrocytes requires activation of the PI 3-kinase pathway but not ERK MAPK..  The Biochemical journal.  389:723-9. 2005
136. NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments..  Journal of immunology (Baltimore, Md. : 1950).  174:5781-8. 2005
137. Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span..  Endocrinology.  146:2920-32. 2005
138. Is serum leptin related to physical function and is it modifiable through weight loss and exercise in older adults with knee osteoarthritis?.  International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.  28:1383-90. 2004
139. Osteoarthritis..  Science of aging knowledge environment : SAGE KE.  2004:-. 2004
140. Aging cartilage and osteoarthritis--what's the link?.  Science of aging knowledge environment : SAGE KE.  2004:-. 2004
141. Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial..  Arthritis and rheumatism.  50:1501-10. 2004
142. Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial..  The American journal of clinical nutrition.  79:544-51. 2004
143. Effects of long-term estrogen replacement therapy on articular cartilage IGFBP-2, IGFBP-3, collagen and proteoglycan levels in ovariectomized cynomolgus monkeys..  Osteoarthritis and cartilage.  12:160-8. 2004
144. Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels..  Arthritis and rheumatism.  48:3419-30. 2003
145. Aging or osteoarthritis: which is the problem?.  Rheumatic diseases clinics of North America.  29:653-73. 2003
146. Systemic and local regulation of articular cartilage metabolism: where does leptin fit in the puzzle?.  Arthritis and rheumatism.  48:3009-12. 2003
147. The Arthritis, Diet and Activity Promotion Trial (ADAPT): design, rationale, and baseline results..  Controlled clinical trials.  24:462-80. 2003
148. The combination of insulin-like growth factor 1 and osteogenic protein 1 promotes increased survival of and matrix synthesis by normal and osteoarthritic human articular chondrocytes..  Arthritis and rheumatism.  48:2188-96. 2003
149. Prolonged treatment of human osteoarthritic chondrocytes with insulin-like growth factor-I stimulates proteoglycan synthesis but not proteoglycan matrix accumulation in alginate cultures..  The Journal of rheumatology.  30:1565-70. 2003
150. Inhibitory effects of insulin-like growth factor-1 and osteogenic protein-1 on fibronectin fragment- and interleukin-1beta-stimulated matrix metalloproteinase-13 expression in human chondrocytes..  The Journal of biological chemistry.  278:25386-94. 2003
151. Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathway..  The Journal of biological chemistry.  278:24577-85. 2003
152. Integrin-mediated adhesion of human articular chondrocytes to cartilage..  Arthritis and rheumatism.  48:110-8. 2003
153. Toward optimal health: the experts discuss osteoarthritis in women [interviewed by Jodi Godfrey Meisler]..  Journal of women's health (2002).  11:759-65. 2002
154. Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1..  Arthritis and rheumatism.  46:2349-57. 2002
155. Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes..  Arthritis and rheumatism.  46:2368-76. 2002
156. Effects of long-term estrogen replacement therapy on osteoarthritis severity in cynomolgus monkeys..  Arthritis and rheumatism.  46:1956-64. 2002
157. The alpha5beta1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitro..  Arthritis and rheumatism.  46:1528-35. 2002
158. Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species..  Arthritis and rheumatism.  46:394-403. 2002
159. CD44 and integrin matrix receptors participate in cartilage homeostasis..  Cellular and molecular life sciences : CMLS.  59:36-44. 2002
160. Integrins and cell signaling in chondrocytes..  Biorheology.  39:119-24. 2002
161. Mechanisms of chondrocyte adhesion to cartilage: role of beta1-integrins, CD44, and annexin V..  Journal of orthopaedic research : official publication of the Orthopaedic Research Society.  19:1122-30. 2001
162. Modifiers of change in physical functioning in older adults with knee pain: the Observational Arthritis Study in Seniors (OASIS)..  Arthritis and rheumatism.  45:331-9. 2001
163. Exercise and weight loss in obese older adults with knee osteoarthritis: a preliminary study..  Journal of the American Geriatrics Society.  48:1062-72. 2000
164. Functional estrogen receptors in adult articular cartilage: estrogen replacement therapy increases chondrocyte synthesis of proteoglycans and insulin-like growth factor binding protein 2..  Arthritis and rheumatism.  43:2081-90. 2000
165. Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease..  Arthritis and rheumatism.  43:2110-20. 2000
166. Aging and the etiopathogenesis and treatment of osteoarthritis..  Rheumatic diseases clinics of North America.  26:547-67. 2000
167. Autocrine stimulation by insulin-like growth factor 1 and insulin-like growth factor 2 mediates chondrocyte survival in vitro..  Arthritis and rheumatism.  43:1552-9. 2000
168. Integrin expression by primary and immortalized human chondrocytes: evidence of a differential role for alpha1beta1 and alpha2beta1 integrins in mediating chondrocyte adhesion to types II and VI collagen..  Osteoarthritis and cartilage.  8:96-105. 2000
169. Chondrocyte integrin expression and function..  Biorheology.  37:109-16. 2000
170. Estrogen replacement therapy modulation of the insulin-like growth factor system in monkey knee joints..  Arthritis and rheumatism.  42:2103-11. 1999
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