Sumoylation and nuclear translocation of S100A4 regulate IL-1beta-mediated production of matrix metalloproteinase-13.
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Overview
publication date
- January 1, 2010
published in
has subject area
- Active Transport, Cell Nucleus
- Amino Acid Substitution
- Cell Nucleus
- Cells, Cultured
- Chondrocytes
- Collagen Type II
- Gene Expression Regulation, Enzymologic
- Humans
- Interleukin-1beta
- Matrix Metalloproteinase 13
- Mutation, Missense
- Promoter Regions, Genetic
- Protein Processing, Post-Translational
- S100 Calcium-Binding Protein A4
- S100 Proteins
- SUMO-1 Protein