GeroScience Journal

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The mouse Social Frailty Index (mSFI): a novel behavioral assessment for impaired social functioning in aging mice. 2024
Quantification of healthspan in aging mice: introducing FAMY and GRAIL.. 46:4203-4215. 2024
Differential mitochondrial bioenergetics and cellular resilience in astrocytes, hepatocytes, and fibroblasts from aging baboons.. 46:4443-4459. 2024
Sex differences in interacting genetic and functional connectivity biomarkers in Alzheimer's disease. 2024
Longitudinal aortic strain, ventriculo-arterial coupling and fatty acid oxidation: novel insights into human cardiovascular aging. 2024
The common marmoset as a translational model of age-related osteoarthritis.. 46:2827-2847. 2024
Association of biological aging with frailty and post-transplant outcomes among adults with cirrhosis.. 46:3287-3295. 2024
Recapitulation of anti-aging phenotypes by global overexpression of PTEN in mice.. 46:2653-2670. 2023
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used.. 46:795-816. 2023
A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment.. 46:665-682. 2023
Lower muscle mitochondrial energetics is associated with greater phenotypic frailty in older women and men: the Study of Muscle, Mobility and Aging.. 46:2409-2424. 2023
Blazing a trail for the clinical use of rapamycin as a geroprotecTOR.. 45:2769-2783. 2023
Changes in oral health during aging in a novel non-human primate model.. 46:1909-1926. 2023
Proteomic changes induced by longevity-promoting interventions in mice.. 46:1543-1560. 2023
Does physical activity moderate the association between shorter leukocyte telomere length and incident coronary heart disease? Data from 54,180 UK Biobank participants.. 46:1331-1342. 2023
Systemic inflammation and biological aging in the Health and Retirement Study.. 45:3257-3265. 2023
Coordinated transcriptional upregulation of oxidative metabolism proteins in long-lived endocrine mutant mice.. 45:2967-2981. 2023
Long-term effects of canagliflozin treatment on the skeleton of aged UM-HET3 mice.. 45:1933-1951. 2023
Geroprotective interventions in the 3xTg mouse model of Alzheimer's disease.. 45:1343-1381. 2023
The transcription regulator ATF4 is a mediator of skeletal muscle aging.. 45:2525-2543. 2023
Effect of Nrf2 loss on senescence and cognition of tau-based P301S mice.. 45:1451-1469. 2023
A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways.. 45:2511-2523. 2023
Four anti-aging drugs and calorie-restricted diet produce parallel effects in fat, brain, muscle, macrophages, and plasma of young mice.. 45:2495-2510. 2023
Pan-primate studies of age and sex. 2023
Testing the evidence that lifespan-extending compound interventions are conserved across laboratory animal model species.. 45:1401-1409. 2023
Recapitulation of anti-aging phenotypes by global, but not by muscle-specific, deletion of PAPP-A in mice.. 45:931-948. 2022
Handgrip strength is associated with learning and verbal fluency in older men without dementia: insights from the NHANES.. 45:1049-1058. 2022
Endpoints for geroscience clinical trials: health outcomes, biomarkers, and biologic age.. 44:2925-2931. 2022
Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop.. 44:2573-2583. 2022
A metabolomic signature of the APOE2 allele.. 45:415-426. 2022
Tissue-specific reductions in mitochondrial efficiency and increased ROS release rates during ageing in zebra finches, Taeniopygia guttata.. 45:265-276. 2022
Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice.. 45:385-397. 2022
Elevated skin senescence in young mice causes delayed wound healing.. 44:1871-1878. 2022
Brain cellular senescence in mouse models of Alzheimer's disease.. 44:1157-1168. 2022
Evaluation of a blood-based geroscience biomarker index in a randomized trial of caloric restriction and exercise in older adults with heart failure with preserved ejection fraction.. 44:983-995. 2022
Einstein-Nathan Shock Center: translating the hallmarks of aging to extend human health span.. 43:2167-2182. 2021
Effect of longevity genetic variants on the molecular aging rate.. 43:1237-1251. 2021
Skeletal muscle mitochondrial DNA copy number and mitochondrial DNA deletion mutation frequency as predictors of physical performance in older men and women.. 43:1253-1264. 2021
Quest for a summary measure of biological age: the health and retirement study.. 43:395-408. 2021
Progression of neuropsychiatric symptoms in young-onset versus late-onset Alzheimer's disease.. 43:213-223. 2021
SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome-the Myhre syndrome.. 43:1481-1496. 2021
DNA methylation age analysis of rapamycin in common marmosets.. 43:2413-2425. 2021
From bedside to battlefield: intersection of ketone body mechanisms in geroscience with military resilience.. 43:1071-1081. 2020
A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin.. 43:1093-1112. 2020
Treatment with a DC-SIGN ligand reduces macrophage polarization and diastolic dysfunction in the aging female but not male mouse hearts.. 43:881-899. 2020
Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice.. 42:801-812. 2020
Age-related changes in the cartilage of the temporomandibular joint.. 42:995-1004. 2020
Primary neuron and astrocyte cultures from postnatal Callithrix jacchus: a non-human primate in vitro model for research in neuroscience, nervous system aging, and neurological diseases of aging.. 43:115-124. 2020
Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice.. 42:333-352. 2019
A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup.. 40:419-436. 2018
Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions.. 40:269-278. 2018
Hydrogen sulfide ameliorates aging-associated changes in the kidney.. 40:163-176. 2018
A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse.. 39:187-198. 2017