I am a physician-scientist in clinical and translational research on aging. My research interests include identifying the mechanisms of sarcopenia and functional loss, and determining the role of metabolism, hormones, diabetes, inactivity, exercise, nutrition, physical therapy, and pharmacological interventions on muscle aging and functional recovery in older adults. Recent research focuses on discovering the pathways that lead to loss of muscle mass and strength, identify therapeutic targets for treatments that improve physical function and independence in older adults, and determining the efficacy of testosterone and resistance exercise for recovery from hip fracture in older women (STEP-HI). I have also been the site PI of large clinical trials in geriatric patients, such as D-CARE, ASPREE, STRIDE Study, REHAB-HFpEF.