Neurobiology of disease
Journal
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Overview
publication venue for
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MRI-based basal forebrain atrophy and volumetric signatures associated with limbic TDP-43 compared to Alzheimer's disease pathology..
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2023
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Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities..
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2022
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CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease..
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2022
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Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage..
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2022
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Multi-transcriptomic analysis points to early organelle dysfunction in human astrocytes in Alzheimer's disease..
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2022
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APOE4 confers transcriptomic and functional alterations to primary mouse microglia..
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2022
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The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease..
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2021
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Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease..
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2021
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Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response..
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2020
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It's complicated: The relationship between sleep and Alzheimer's disease in humans..
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2020
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Microglia and astrocyte dysfunction in parkinson's disease..
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2020
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Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease..
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2020
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Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2..
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2020
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LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease..
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2019
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Heritability and genetic variance of dementia with Lewy bodies..
492-501.
2019
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Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration..
98-106.
2018
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TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunities..
83-93.
2018
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Ifngr1 and Stat1 mediated canonical Ifn-γ signaling drives nigrostriatal degeneration..
133-141.
2017
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Alzheimer's brains show inter-related changes in RNA and lipid metabolism..
1-13.
2017
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Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies..
55-62.
2016
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Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance..
111-121.
2015
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A spectrum of exercise training reduces soluble Aβ in a dose-dependent manner in a mouse model of Alzheimer's disease..
218-224.
2015
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Neuroprotective effects of urate are mediated by augmenting astrocytic glutathione synthesis and release..
574-579.
2015
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Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration..
345-58.
2014
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Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases..
129-40.
2013
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Maintaining energy homeostasis is an essential component of Wld(S)-mediated axon protection..
69-79.
2013
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Creatine pretreatment protects cortical axons from energy depletion in vitro..
47:184-93.
2012
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Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways..
45:1018-30.
2011
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Core features of frontotemporal dementia recapitulated in progranulin knockout mice..
45:395-408.
2011
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Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging..
43:46-51.
2010
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Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations..
40:348-59.
2010
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Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex..
37:764-71.
2010
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Traumatic brain injury reduces soluble extracellular amyloid-β in mice: a methodologically novel combined microdialysis-controlled cortical impact study..
40:555-64.
2010
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Anti-PrP Mab 6D11 suppresses PrP(Sc) replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivo..
34:267-78.
2009
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Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology..
34:163-77.
2009
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Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease..
35:426-32.
2009
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Biomarkers of Alzheimer's disease..
35:128-40.
2008
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FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons..
33:81-8.
2008
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MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity..
26:312-22.
2007
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Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex..
28:184-96.
2007
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Caspase-3 deficiency during development increases vulnerability to hypoxic-ischemic injury through caspase-3-independent pathways..
22:523-37.
2006
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Hypoxic injury of isolated axons is independent of ionotropic glutamate receptors..
25:284-90.
2006
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Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease..
24:506-15.
2006
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Production and characterization of astrocyte-derived human apolipoprotein E isoforms from immortalized astrocytes and their interactions with amyloid-beta..
19:66-76.
2005
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Role of caspase-3 in ethanol-induced developmental neurodegeneration..
20:608-14.
2005
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Diffusion tensor imaging detects age-dependent white matter changes in a transgenic mouse model with amyloid deposition..
15:640-7.
2004
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Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity..
14:303-17.
2003
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Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice..
14:10-8.
2003
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Apolipoprotein E protects against NMDA excitotoxicity..
11:214-20.
2002
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A presenilin 1 mutation associated with familial frontotemporal dementia inhibits gamma-secretase cleavage of APP and notch..
9:269-73.
2002
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Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains..
9:11-23.
2002
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Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease..
9:305-18.
2002
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The modulation of cellular susceptibility to oxidative stress: protective and destructive actions of Cu,Zn-superoxide dismutase..
10:234-46.
2002
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Oxidative stress and genetics in the pathogenesis of Parkinson's disease..
7:240-50.
2000
Identity
International Standard Serial Number (ISSN)